97603-53-7 Usage
Uses
Used in Pharmaceutical Industry:
PDPH is used as a potential anticancer agent for its ability to inhibit kinase enzymes involved in cell proliferation, offering a therapeutic approach to combat cancer.
Used in Neurodegenerative Disorder Treatment:
PDPH is utilized as a potential therapeutic agent for treating various neurodegenerative disorders, highlighting its potential in addressing neurological conditions.
Used in Synthesis of Biologically Active Compounds:
PDPH serves as a building block for the synthesis of other biologically active compounds, contributing to the development of new pharmaceuticals and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 97603-53-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,6,0 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 97603-53:
(7*9)+(6*7)+(5*6)+(4*0)+(3*3)+(2*5)+(1*3)=157
157 % 10 = 7
So 97603-53-7 is a valid CAS Registry Number.
97603-53-7Relevant academic research and scientific papers
Preparation of Triazolopyrimidines as Potential Antiasthma Agents
Medwid, Jeffrey B.,Paul, Rolf,Baker, Jannie S.,Brockman, John A.,Du, Mila T.,et al.
, p. 1230 - 1241 (2007/10/02)
With the use of the human basophil histamine release assay, 5-aryl-2-aminotriazolopyrimidines were found to be active as mediator release inhibitors.These compounds were prepared by reacting arylamidines with sodium ethyl formylacetate or with ethyl propiolate to give pyrimidinones.Treatment with phosphorus oxychloride gave a chloropyrimidine, which was converted to a hydrazinopyrimidine with hydrazine.Cyclization, using cyanogen bromide, gave the triazolopyrimidines, after a Dimroth rearrangement.Following a structure-activity evaluation, the5--2-amino (8-10), 5-(3-bromophenyl)-2-amino (8-13), 5--2-amino (8-11), and 5-(4-pyridinyl)-2-amino (6-7) compounds were found to have the best activity.They were chosen for further pharmacological and toxicological study.
