97694-39-8

Upstream product

• 35810-59-4 3-C-Ethynyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 100-44-7 benzyl chloride 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 100-39-0 benzyl bromide 
• 35810-59-4 (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-ethynyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 

Downstream Products

• 97694-40-1 3-O-benzyl-3-C-ethynyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose 
• 1351933-22-6 (R)-1-((3aR,5R,6R,6aR)-6-(benzyloxy)-6-ethynyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol 
• 1351933-26-0 (3aR,5R,6R,6aR)-6-(benzyloxy)-6-ethynyl-2,2-dimethyl-5-((R)-oxiran-2-yl)tetrahydrofuro[2,3-d][1,3]dioxole 
• 1351933-29-3 (R)-1-((3aR,5R,6R,6aR)-6-(benzyloxy)-6-ethynyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)prop-2-en-1-ol 
• 1351933-32-8 (3aR,4aR,5R,8aR,8bR)-8a-(benzyloxy)-2,2-dimethyl-8-methylene-3a,4a,5,8,8a,8bhexahydrobenzofuro[2,3-d][1,3]dioxol-5-ol 
• 1351933-35-1 (3aR,4aS,8aS,8bR)-8a-(benzyloxy)-2,2-dimethyl-8-methylene-4a,8,8a,8b-tetrahydrobenzofuro[2,3-d][1,3]dioxol-5(3aH)-one 

Relevant academic research and scientific papers

A tandem enyne/ring closing metathesis approach to 4-methylene-2- cyclohexenols: An efficient entry to otteliones and loloanolides

A short and efficient approach to a 4-methylene-2-cyclohexenone substructure present in otteliones and loloanolides is described. This strategy involves a tandem enyne/ring closing metathesis as the key reaction to construct this labile core unit.

ANTHRACYCLINONES. PART 3. USE OF DI-ISOPROPYLIDENE-D-GLUCOSE AND A MODIFIED MARSCHALK REACTION TO INTRODUCE A TERTIARY CARBINOL FUNCTION INTO RING D OF ANTHRACYCLINONES

Reaction of 3-C-ethynyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose (2b) with leuco-quinizarin (4) in alkaline solution gave a mixture of (5S)- and (5R)-3-C-ethynyl-1,2-O-isopropylidene-5-(quinizarin-2-yl)-α-D-ribofuranose (11a) and (11b) respe