97749-71-8Relevant academic research and scientific papers
13C CPMAS NMR as a tool for full structural description of 2-phenyl substituted imidazoles that overcomes the effects of fast tautomerization
Burdzhiev, Nikola,Ahmedova, Anife,Borrisov, Boris,Graf, Robert
, (2020/09/04)
Tautomerization of 2-phenylimidazolecarbaldehydes has not been studied in detail so far, although this process is a well-known phenomenon for imidazole derivatives. That is why we focus our study on a series of 2-phenylimidazolecarbaldehydes and their par
Highly efficient, environment-friendly, one-pot synthesis of 2-substituted 4-formylimidazoles from 4-acylaminoisoxazoles
Gao, Feng,Tian, Xin-Chuan,Qu, Xiao-Xia,Wang, Dan,Pu, Dong
, p. 65 - 70 (2015/02/18)
A highly efficient and environment-friendly one-pot synthesis of 2-substituted 4-formylimidazoles was accomplished. Raney nickel catalyzed hydrogenation of 4-acylaminoisoxazoles in ethanol, followed by sodium hydroxide promoted recyclization of the ring-opened intermediates, afforded the functionalized imidazoles.
Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones
Dhainaut, Alain,Tizot, André,Raimbaud, Eric,Lockhart, Brian,Lestage, Pierre,Goldstein, Solo
, p. 2165 - 2175 (2007/10/03)
A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi
Nitrone compounds
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, (2008/06/13)
A compound selected from those of formula (1): wherein W represents aryl, arylalkyl, heteroaryl, or heteroarylalkyl, each being optionally substituted, R1 represents alkyl, alkenyl, alkynyl, aryl, cycloalkyl, arylalkyl, or cycloalkylalkyl, each being opti
Imidazotriazines as Potential Antiasthma Agents
Paul, Rolf,Brockman, John A.,Hallett, W. A.,Hanifin, John W.,Tarrant, M. Ernestine,et al.
, p. 1704 - 1716 (2007/10/02)
By using inhibition of histamine release from antigen-challenged, sensitized human basophils as a means of identifying a potentialy prophylactic drug for the treatment of asthma, a series of substituted imidazotriazines were found, which wer
