53292-67-4

Usage

Physical form

White to off-white crystalline powder

Use in pharmaceutical development

As an intermediate in the synthesis of various drugs

Therapeutic potential

Antibacterial and antifungal properties, treatment of inflammatory and autoimmune diseases

Biological significance

Inhibition of certain enzymes

Upstream product

• 67-56-1 methanol 
• 96-26-4 dihydroxyacetone 
• 123-11-5 4-methoxy-benzaldehyde 
• 62147-49-3 1,3-dihydroxyacetone dimer 
• 22265-37-8 4-methoxybenzamidine 
• 874-90-8 4-methoxybenzonitrile 

Downstream Products

• 97749-71-8 2-(4-methoxyphenyl)-1H-imidazole-4⁽⁵⁾-carbaldehyde 
• 102152-25-0 (S)-2-<4-<3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-2-hydroxypropoxy>phenyl>-4-(morpholinomethyl)imidazole 
• 102151-64-4 2-(4-hydroxyphenyl)-4-(morpholinomethyl)imidazole 
• 97749-71-8 2-(4-Methoxy-phenyl)-3H-imidazole-4-carbaldehyde 
• 102151-63-3 2-(4-methoxyphenyl)-4-(morpholinomethyl)imidazole 

Relevant academic research and scientific papers

13C CPMAS NMR as a tool for full structural description of 2-phenyl substituted imidazoles that overcomes the effects of fast tautomerization

Tautomerization of 2-phenylimidazolecarbaldehydes has not been studied in detail so far, although this process is a well-known phenomenon for imidazole derivatives. That is why we focus our study on a series of 2-phenylimidazolecarbaldehydes and their par

2-Phenyl-4-(aminomethyl)imidazoles as Potential Antipsychotic Agents. Synthesis and Dopamine D2 Receptor Binding

A series of 2-phenyl-4-(aminomethyl)imidazoles were designed as conformationally restricted analogs of the dopamine D2 selective benzamide antipsychotics.The title compounds were synthesized and tested for blockade of YM-09151 binding in cloned African green monkey dopamine D2 receptor preparations.The binding affinity data thus obtained were compared against that of the benzamides and a previously described series of 2-phenyl-5-(aminomethyl)pyrroles.

BETA-BLOCKING SUBSTITUTED IMIDAZOLES

Novel substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and β-adrenergic blocking activity.

BETA-ADRENERGIC BLOCKING IMIDAZOLYLPHENOXY PROPANOLAMINES

Substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and β-adrenergic blocking activity. STR1

β1-Selective Adrenoceptor Antagonists: Examples of the 2-phenyl>imidazole Class. 2

An attempt to develop a highly cardioselective β-adrenoceptor antagonist devoid of intrinsic sympathomimetic activity (ISA) focused on exploring structure-activity relationships around (S)--amino>-2-hydroxypropoxy>phen