97855-75-9

Upstream product

• 110715-81-6 (+)-(1S,4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethylnaphthalen-1-ol 
• 108-94-1 cyclohexanone 
• 97868-04-7 (2R,4aS,8aS)-(-)-1,2,3,4,4a,5,6,7,8,8a-decahydro-2α-hydroxy-5,5,8aβ-trimethyl-1-oxonaphthalene 
• 97855-67-9 (-)-(2R,4aS,8aS)-2-bromo-3,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalen-1(2H)-one 
• 97855-69-1 methyl (+)-(1S,2S)-2-allyl-1,3,3-trimethylcyclohexanecarboxylate 
• 97855-71-5 (+)-(1S,2S)-2-allyl-1,3,3-trimethylcyclohexanecarbaldehyde ethylene acetal 
• 97855-68-0 (-)-(1S,2S)-2-(3-hydroxypropyl)-1,3,3-trimethylcyclohexanecarboxylate 
• 125265-52-3 (1S,2S)-1,3,3-Trimethyl-2-(3-oxo-propyl)-cyclohexanecarboxylic acid methyl ester 
• 97855-72-6 ((1S,2S)-2-[1,3]Dioxolan-2-yl-2,6,6-trimethyl-cyclohexyl)-acetaldehyde 
• 110654-77-8 2-[2-((1S,2S)-2-[1,3]Dioxolan-2-yl-2,6,6-trimethyl-cyclohexyl)-ethyl]-cyclohexanone 
• 97855-73-7 2-[2-((1S,2S)-2-[1,3]Dioxolan-2-yl-2,6,6-trimethyl-cyclohexyl)-eth-(E)-ylidene]-cyclohexanone 
• 110654-68-7 (1S,2S)-2-Allyl-1,3,3-trimethyl-cyclohexanecarbaldehyde 
• 97855-70-4 (+)-(1S,2S)-(2-allyl-1,3,3-trimethylcyclohexyl)methanol 
• 110715-80-5 (-)-(1S,8aS)-1,2,3,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalen-1-ol 

Downstream Products

• 97906-41-7 methyl (1'S,2'S)-3-<1',3',3'-trimethyl-2'-<2-(2-oxocyclohex-3-enyl)ethyl>cyclohexyl>prop-2(E)-enoate 
• 7721-78-0 (+)-atisirene 

Relevant academic research and scientific papers

An Enantioselective Total Synthesis of (+)-Atisirene by Intramolecular Double Michael Reaction

1,6-Conjugate addition of 2-methoxybenzylmagnesium bromide to 4-methylene-3,5,5-trimethylcyclohex-2-enone (7), followed by hydrocyanation, gave (+/-)-(1RS,2SR)-2--1,3,3-trimethyl-5-oxocyclohexanecarbonitrile (9), which was conver

INTRAMOLECULAR DOUBLE MICHAEL REACTION III, STEREOSELECTIVE CHIRAL SYNTHESIS OF ATISIRAN-15-ONE

Atisiran-15-one (5) was stereoselectively synthesized starting from the ketone (10) through the intramolecular double Michael reaction.