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Perloline, also known as 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, is a synthetic chemical compound with potential neuroprotective properties. It has been studied for its ability to modulate the activity of the N-methyl-D-aspartate (NMDA) receptor, which is involved in various neurological processes, including learning and memory. Perloline has shown promise in preclinical studies for its potential to protect neurons from damage and degeneration, making it a subject of interest in the development of treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's. However, it is important to note that further research is needed to fully understand its mechanisms of action and potential therapeutic applications.

979-68-0

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979-68-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 979-68-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,7 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 979-68:
(5*9)+(4*7)+(3*9)+(2*6)+(1*8)=120
120 % 10 = 0
So 979-68-0 is a valid CAS Registry Number.

979-68-0Downstream Products

979-68-0Relevant academic research and scientific papers

The Synthesis of Perloline, 6-(3,4-Dimethoxyphenyl)-5-hydroxy-5,6-dihydrobenzonaphthyridin-4(3H)-one

Prager, Rolf H.,Were, Stephen T.

, p. 1441 - 1453 (2007/10/02)

Dehydroperloline is obtained in high overall yield by an intramolecular cyclization of the benzyne generated from 4-(2-bromophenyl)-N-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (21), by use of lithium hexamethyldisilazide.A benzyne inte

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