97915-68-9Relevant academic research and scientific papers
Zn(II) coordination compounds derived from 4-acyl pyrazolones and 1,10 phenanthroline: Syntheses, crystal structures, spectral analysis and DNA binding studies
Jadeja,Chhatrola, Mitesh,Gupta, Vivek K.
, p. 117 - 126 (2013)
A new series of three Zn(II) coordination complexes [Zn(MCPMPAC) 2H2O] = complex 1, [Zn(PMPAC)2H2-O] = complex 2 and [Zn(PMPAC)2(phen)] = complex 3 (MCPMPAC = 4-acyl-3-methyl-1-(3-chlorophenyl) pyrazolone-5-one, PMPAC = 4-acyl-3-methyl-1-phenyl pyrazolone-5-one, Phen=1,10 phenanthroline) has been synthesized and characterized. The structural features of synthesized complexes were determined by metal estimation, molar conductivity, IR, UV-Vis, NMR and single crystal X-ray study. The conductivity data confirm the non-electrolytic nature of the complexes. The single crystal analyses of the complexes show that the Zn(II) ion is five-coordinated with water molecule at axial position in case of 1 and 2 whereas, six-coordinated with phenanthroline ligand in case of 3. Binding of the synthesized complexes with calf thymus DNA (CT-DNA) was studied by spectroscopic methods and viscosity measurements. Experimental results suggest that the zinc complexes have the ability to form adducts with DNA and to distort the double helix by changing the base stacking.
Synthesis and spectral characterization of Cu(II) complexes of some thio-Schiff bases of acyl pyrazolone analogues
Yadav, Ravindra J.,Vyas, Komal M.,Jadeja
experimental part, p. 1820 - 1831 (2010/11/03)
A series of tridentate pyrazolone-based thio-Schiff bases were synthesized by the interaction of 4-acyl/aroyl pyrazolones with thiosemicarbazide in an ethanolic medium. All of these ligands were characterized on the basis of elemental analysis, infrared (IR), 1H- and 13C-NMR data. Nuclear magnetic resonance (NMR) suggests the amine-one form of ligand in solution at room temperature. Copper Schiff-base complexes, [Cu(L)(H2O)], have been prepared by the interaction of the aqueous solution of copper sulfate pentahydrate with hot ethanolic solution of the appropriate ligand. The resulting complexes have been characterized by elemental analysis, metal content determination, molar conductance, fast atom bombardment mass spectra, magnetic measurements, thermogravimetric analysis (TGA), IR, and electronic spectral studies. Thermal stability, heat capacity, and activation energy of thermal degradation for these complexes were determined by TGA, differential thermal analysis, and differential scanning calorimetry. Suitable structures are proposed for these complexes.
