98-22-6

Usage

Uses

Used in Industrial Applications:
2,6-DIBROMO-4-TERT-BUTYL-PHENOL is used as a biocide and preservative for inhibiting the growth of bacteria, fungi, and algae in various industrial processes. Its effectiveness in controlling microbial growth makes it a valuable component in the production of materials that require protection against microbial contamination.
Used in Agricultural Applications:
In agriculture, 2,6-DIBROMO-4-TERT-BUTYL-PHENOL is used as a biocide to protect crops from fungal infections and to control the growth of algae in irrigation systems. Its ability to inhibit the growth of harmful microorganisms contributes to maintaining crop health and improving agricultural productivity.
Used in Water Treatment:
2,6-DIBROMO-4-TERT-BUTYL-PHENOL is employed in water treatment processes to control the growth of bacteria, fungi, and algae in water systems. Its use helps to ensure the quality of water and prevent the spread of waterborne diseases.
Used in Paint and Coating Industry:
In the paint and coating industry, 2,6-DIBROMO-4-TERT-BUTYL-PHENOL is used as a preservative to prevent the growth of microorganisms that can cause spoilage and deterioration of paint products. Its inclusion in paint formulations helps to extend the shelf life and maintain the quality of the paint.
Used in Textile Industry:
2,6-DIBROMO-4-TERT-BUTYL-PHENOL is utilized in the textile industry as a biocide to protect fabrics from microbial contamination and to prevent the growth of mold and mildew. Its use in textile treatments helps to enhance the durability and longevity of textile products.
Used in Pulp and Paper Industry:
In the pulp and paper industry, 2,6-DIBROMO-4-TERT-BUTYL-PHENOL is used as a biocide to control the growth of microorganisms that can cause spoilage and deterioration of paper products. Its application in the production process helps to maintain the quality and integrity of paper and pulp materials.

InChI:InChI=1/C10H12Br2O/c1-10(2,3)6-4-7(11)9(13)8(12)5-6/h4-5,13H,1-3H3

Upstream product

• 98-54-4 para-tert-butylphenol 
• 90-15-3 α-naphthol 
• 110387-88-7 2,6-dibromo-4-nitro-4-tbutyl-2,5-cyclohexadien-1-one 
• 7726-95-6 bromine 

Downstream Products

• 61305-82-6 2,6-Dibrom-4-hydroxy-4-tert.-butyl-cyclohexa-2,5-dienon 
• 85903-12-4 2,6-dibromo-4-tert-butylphenoxytriethylsilane 
• 38475-55-7 3-bromo-5-tert-butyl-1,2-quinone 
• 19643-45-9 2,6-dibromo-1,4-benzoquinone 
• 110190-11-9 2-Bromo-6-(4-tert-butyl-phenoxy)-[1,4]benzoquinone 
• 110387-88-7 2,6-dibromo-4-nitro-4-tbutyl-2,5-cyclohexadien-1-one 
• 17154-35-7 2,6-dibromo-4-tert-butylphenyl trimethylsilyl ether 
• 163273-44-7 (3-bromo-5-tert-butyl-2-methoxyphenyl)diphenylphosphine 
• 163273-46-9 5-tert-butyl-3-(diphenylphosphino)-2-hydroxybenzaldehyde 
• 163273-45-8 5-tert-butyl-3-(diphenylphosphino)-2-methoxybenzaldehyde 
• 61306-19-2 Acetic acid 3,5-dibromo-1-tert-butyl-4-oxo-cyclohexa-2,5-dienyl ester 
• 61306-14-7 Propionic acid 3,5-dibromo-1-tert-butyl-4-oxo-cyclohexa-2,5-dienyl ester 
• 61306-28-3 Isobutyric acid 3,5-dibromo-1-tert-butyl-4-oxo-cyclohexa-2,5-dienyl ester 
• 61306-23-8 Butyric acid 3,5-dibromo-1-tert-butyl-4-oxo-cyclohexa-2,5-dienyl ester 

Relevant academic research and scientific papers

Selective Bromination of β-Positions of Porphyrin by Self-Catalytic Behaviour of VOTPP: Facile Synthesis, Electrochemical Redox Properties and Catalytic Application

Oxidovanadium(IV) complex of β-octabromo-meso-tetraphenylporphyrin, {[VIVO(TPPBr8)], 2} was synthesized by self-catalytic oxidative bromination of meso-tetraphenylporphyrinatooxidovanadium(IV) {[VIVO(TPP), 1} in excellent yield under mild conditions at 25 °C and its structure was confirmed by single crystal X-ray study. UV-Vis and 1H NMR spectra further confirmed that the meso-phenyl rings are not brominated and thus emphasizes on the selectivity as well as synthetic importance of this catalytic method. In the presence of substrates e. g. phenol derivatives, 1 biomimics the vanadium bromoperoxidase (VBPO) enzyme and catalyses the oxidative bromination of substrates in water at 25 °C. Remarkably, 2 also catalyses the oxidative bromination of phenol derivatives under similar reaction conditions with very high turnover frequency (TOF) values (ca. 29 s?1) along with its recyclability. It was found that 2 showed superior catalytic performance as compared to 1 because of its electron deficient nature due to electron withdrawing bromo substituents and robust saddle shaped nonplanar structure (further supported by DFT studies).

Green halogenation reactions for (hetero)aromatic ring systems in alcohol, water, or no solvent

A new method of brominating aromatic and heteroaromatic ring systems is investigated. The combination of hydrobromic acid as the halogen source, hydrogen peroxide as the oxidant, and ethanol, water, or no solvent are evaluated as greener conditions than those that have been previously published. The new conditions give high yields and good regioselectivity for a variety of substrates when the ring is activated by electron-donating groups or heteroatoms. Phenols, anisole, thiophenes, and pyrrole give comparable or superior results when compared to a traditional bromination by N-bromosuccinimide in tetrahydrofuran. Other nitrogen-containing heterocycles do not react under the conditions because they are protonated and hence deactivated; similarly, substrates with electron-withdrawing groups are not brominated. The reaction is very tolerant of a variety of functional groups.

Microflow fluorinations of benzynes: Efficient synthesis of fluoroaromatic compounds

Fluorinated aromatic compounds are found in a variety of biologically active compounds, including clinical drugs and agrochemicals. Therefore, the synthesis of aryl fluorides is particularly important in the medicinal and process chemistry fields. In this

Selective and efficient generation of ortho-brominated para-substituted phenols in ACS-grade methanol

The mono ortho-bromination of phenolic building blocks by NBS has been achieved in short reaction times (15-20 min) using ACS-grade methanol as a solvent. The reactions can be conducted on phenol, naphthol and biphenol substrates, giving yields of >86% on gram scale. Excellent selectivity for the desired mono ortho-brominated products is achieved in the presence of 10 mol % para-TsOH, and the reaction is shown to be tolerant of a range of substituents, including CH3/ F,and NHBoc.

Binuclear complexes of Ni(i) from 4-terphenyldithiophenol

Binuclear complexes of Ni(i) have been prepared from a 4-terphenyldithiophenol ligand. Steric effects were found to determine the formation of coordination isomeric structures that differ in the nature of metal-to-ligand bonding. Coordination of spatially

Environmentally benign electrophilic and radical bromination 'on water': H2O2-HBr system versus N-bromosuccinimide

A H2O2-HBr system and N-bromosuccinimide in an aqueous medium were used as a 'green' approach to electrophilic and radical bromination. Several activated and less activated aromatic molecules, phenylsubstituted ketones and styrene were efficiently brominated 'on water' using both systems at ambient temperature and without an added metal or acid catalyst, whereas various non-activated toluenes were functionalized at the benzyl position in the presence of visible light as a radical activator. A comparison of reactivity and selectivity of both brominating systems reveals the H2O2-HBr system to be more reactive than NBS for benzyl bromination and for the bromination of ketones, while for electrophilic aromatic substitution of methoxy-substituted tetralone it was higher for NBS. Also, higher yields of brominated aromatics were observed when using H2O2-HBr 'on water'. Bromination of styrene reveals that not just the structure of the brominating reagent but the reaction conditions: amount of water, organic solvent, stirring rate and interface structure, play a key role in defining the outcome of bromination (dibromination vs bromohydroxylation). In addition, mild reaction conditions, a straightforward isolation procedure, inexpensive reagents and a lower environment impact make aqueous brominating methods a possible alternative to other reported brominating protocols.

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.

Binucleating ligands: Synthesis of acyclic achiral and chiral Schiff base-pyridine and Schiff base-phosphine ligands

5-tert-Butyl-3-(2′-pyridyl)salicyaldehyde and 5-tert-butyl-3-(diphenylphosphino)salicyaldehyde were synthesized from 4-tert-butylphenol in good overall yields. Condensation of the salicyaldehydes with 2,3-diamino-2,3-dimethylbutane afforded the desired dinucleating Schiff base-pyridine and Schiff base-phosphine ligands, respectively. 5-tert-Butyl-3-(2′-pyridyl)salicyaldehyde reacted with optically active 1,2-diaminocyclohexanes to give chiral dinucleating Schiff base-pyridine ligands.

Synthesis of acyclic dinucleating Schiff base-pyridine and Schiff base-phosphine ligands

5-tert-butyl-3-pyridyl-salicyaldehyde and 5-tert-butyl-3-diphenylphosphino-salicyaldehyde have been synthesized from 4-tert-butylphenol in good overall yields. Condensation of the salicyaldehydes with 2,3-diamino-2,3-dimethylbutane afforded the desired dinucleating Schiff base-pyridine and Schiff base-phosphine ligands respectively.