98006-90-7

Basic information

• Product Name: 2-Bromo-5-methylpyrazine
• Synonyms: Pyrazine, 2-bromo-5-methyl-
• CAS NO: 98006-90-7
• Molecular Formula: C₅H₅BrN₂
• Molecular Weight: 173.02
• Product Categories: Pyrazines, Pyrimidines & Pyridazines;Halides
• Mol File: 98006-90-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 198℃
• Flash Point: 74℃
• Appearance: /
• Density: 1.596
• Vapor Pressure: 0.511mmHg at 25°C
• Refractive Index: 1.558
• PKA: -0.36±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-5-methylpyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-methylpyrazine(98006-90-7)
• EPA Substance Registry System: 2-Bromo-5-methylpyrazine(98006-90-7)

Safety Data

• Hazardous Substances Data: 98006-90-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H5BrN2/c1-4-2-8-5(6)3-7-4/h2-3H,1H3

Upstream product

• 5521-55-1 2-methylpyrazin-5-carboxylic acid 
• 5521-58-4 5-methylpyrazin-2-amine 
• 5521-57-3 5‐methylpyrazine-2-carboxamide 
• 41110-33-2 5-methylpyrazine-2-carboxylic acid methyl ester 

Downstream Products

• 1177420-26-6 t-Butyl 2-(5-methylpyrazin-2-yl]-1H-pyrrole-1-carboxylate 
• 1323075-51-9 1-[(3-methyl-1,2-oxazol-4-yl)carbonyl]-10a-(5-methylpyrazin-2-yl)-7-(pyridin-3-yl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrrolo[1,2-d]pyrazin-5-one 
• 1323077-53-7 2,2,2-trichloro-1-{1-[2-(5-methylpyrazin-2-yl)-2-oxoethyl]-1H-pyrrol-2-yl}ethanone 
• 1323077-54-8 1-{4-bromo-1-[2-(5-methylpyrazin-2-yl)-2-oxoethyl]-1H-pyrrol-2-yl}-2,2,2-trichloroethanone 
• 1323077-56-0 methyl 4-bromo-1-[2-(5-methylpyrazin-2-yl)-2-oxoethyl]-1H-pyrrole-2-carboxylate 
• 1323077-57-1 7-bromo-10a-(5-methylpyrazin-2-yl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrrolo[1,2-d]pyrazin-5-one 
• 1323077-60-6 10a-(5-methylpyrazin-2-yl)-7-(pyridin-3-yl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrrolo[1,2-d]pyrazin-5-one 
• 1323077-52-6 1-(5-methylpyrazin-2-yl)-2-(1H-pyrrol-1-yl)ethanone 
• 1346627-27-7 tert-butyl 4-(2-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)benzo[d]thiazol-6-yl)-5,6-dihydropyridine-1(2H)carboxylate 
• 1391082-00-0 (S)-5-(1-methanesulfonyl-1,2,3,6-tetrahydropyridin-4-yl)-2-methyl-2-[1-(5-methylpyrazin-2-yl)piperidin-4-yl]-2,3-dihydrofuro[2,3-c]pyridine 
• 1395896-87-3 (S)-N,N-dibenzyl-5-(5-methylpyrazin-2-yl)chroman-3-amine 
• 1395896-79-3 (S)-N-(5-(5-methylpyrazin-2-yl)chroman-3-yl)-6-(2,2,2-trifluoroethoxy)nicotinamide 
• 1395896-80-6 (S)-N-(5-(5-methylpyrazin-2-yl)chroman-3-yl)-6-((2,2,2-trifluoroethoxy)methyl)nicotinamide 
• 1395896-88-4 (S)-5-(5-methylpyrazin-2-yl)chroman-3-amine 

Relevant articles and documents

Synthesis and Characterization of 2-(2-Pyridinyl)pyrazine and 2,2′-Bipyrazine Derivatives

A convenient and high yield preparation of derivatives of 2-(2-pyridinyl)pyrazine and derivatives of 2,2′-bipyrazine compounds from their derivatives of bromopyrazine using Stille coupling is reported. X-ray structures, elemental analyses, 1H, 13C-NMR, and mass spectral data of the compounds are given.