98057-60-4

Upstream product

• 117924-33-1 di-tert-butyl N,N-diethylphosphoramidite 
• 108-95-2 phenol 
• 137348-86-8 di-tert-butyl diisopropylphosphoramide 
• 110107-26-1 Phosphorous acid di-tert-butyl ester phenyl ester 

Downstream Products

• 124982-91-8 tetra-t-butyl (2-hydroxy-1,3-phenylene)bis(phosphonate) 
• 124982-89-4 di-t-butyl 2-(di-t-butoxyphosphinyl)phenyl phosphate 
• 98057-61-5 di-t-butyl (2-hydroxyphenyl) phosphonate 

Relevant academic research and scientific papers

Di-tert-butyl N,N-Diethylphosphoramidite. A New Phosphitylating Agent for the Efficient Phosphorylation of Alcohols

Alkyl and aryl di-tert-butyl phosphates were prepared in high yields by the 1H-tetrazole-promoted phosphitylation of alkyl and aryl alcohols with di-tert-butyl N,N-diethylphosphoramidite, followed by oxidation of the resultant alkyl and aryl di-tert-butyl

Phosphonate-free phosphorylation of alcohols using bis-(tert-butyl) phosphoramidite with imidazole·hydrochloride and imidazole as the activator

A variety of commercially available alcohols were converted to their bis-(tert-butyl) protected mono-phosphate pro-drugs. The improved procedure uses the unique combination of imidazole·hydrochloride and imidazole as the activator to suppress the formatio