98061-62-2Relevant academic research and scientific papers
Synthesis of dihydroindoles and tetrahydroquinolines by the intramolecular diels-alder reaction of N-alkenylated 2-acylamino-3-furancarbonitriles
Maruoka, Hiroshi,Okabe, Fumi,Koutake, Yoshimichi,Masumoto, Eiichi,Fujioka, Toshihiro,Yamagata, Kenji
experimental part, p. 1467 - 1484 (2010/12/24)
An approach to dihydroindoles and tetrahydroquinolines from N-alkenylated 2-acylamino-3-furancarbonitriles via a [4 + 2] cycloaddition reaction is described. Thermal treatment of N-alkenylated 2-acylamino-3-furancarbonitriles 5ad, 6ad, 9ad, and 10ad, whic
Studies on Heterocyclic Enaminonitriles. VI. Synthesis of 2-Amino-3-cyano-4,5-dihydrofurans
Matsuda, Takumi,Yamagata, Kenji,Tomioka, Yukihiko,Yamazaki, Motoyoshi
, p. 937 - 943 (2007/10/02)
Malononitrile reacts with 2-chloroethanol and 1-chloro-2-propanol (or 2-methyloxirane) in the presence of sodium ethoxide to give 2-amino-3-cyano-4,5-dihydrofuran (Ia) and 2-amino-3-cyano-5-methyl-4,5-dihydrofuran (Ib), respectively.The reaction of malono
