98114-61-5

Basic information

• Product Name: (Z)-POTASSIUMBUTANEDIAZOTATE
• Synonyms: (Z)-POTASSIUMBUTANEDIAZOTATE
• CAS NO: 98114-61-5
• Molecular Formula: C₃H₇N₂O*K
• Molecular Weight: 126.19878
• Mol File: 98114-61-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 138.7°C at 760 mmHg
• Flash Point: 37.7°C
• Appearance: /
• Vapor Pressure: 2.78mmHg at 25°C
• CAS DataBase Reference: (Z)-POTASSIUMBUTANEDIAZOTATE(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-POTASSIUMBUTANEDIAZOTATE(98114-61-5)
• EPA Substance Registry System: (Z)-POTASSIUMBUTANEDIAZOTATE(98114-61-5)

Safety Data

• Hazardous Substances Data: 98114-61-5(Hazardous Substances Data)

Usage

General Description

(Z)-POTASSIUMBUTANEDIAZOTATE, also known as potassium butanedioate, is a chemical compound with the molecular formula C4H5N2O2K. It is a salt form of butanedioic acid (succinic acid) and is commonly used as a food additive and preservative. The compound exists in a zwitterionic form and is often used to enhance the flavor and shelf life of various food products, particularly in the meat industry. It is also used as a buffering agent in pharmaceuticals and can be found in some skincare products. Additionally, (Z)-POTASSIUMBUTANEDIAZOTATE has been studied for its potential inhibitory effects on cancer cells, making it a topic of interest in the fields of oncology and medicinal chemistry.

InChI:InChI=1/C3H7N2O.K/c4-5-2-1-3-6;/h4H,1-3H2;/q-1;+1/b5-4+;

Upstream product

• 5457-56-7 N-n-butyl-N-nitroso-4-toluenesulfonamide 
• 33469-51-1 N-Nitroso-N-propyl-p-toluenesulfonamide 

Downstream Products

• 71-23-8 propan-1-ol 
• 67-63-0 isopropyl alcohol 
• 22293-25-0 n-propyl azide 
• 691-57-6 2-azidopropane 

Relevant articles and documents

Mutagenicity of isomeric alkanediazotates, precursors for ultimate alkylating species of carcinogenic N-nitroso compounds

Alkanediazohydroxides are common key intermediates in carcinogenesis and mutagenesis of N-nitroso compounds, which are widely found in human environment. Mutagenicity of (E)- and (Z)-potassium alkanediazotates, as precursors of corresponding alkanediazohydroxides were evaluated to investigate the effect of geometric isomerism and also the effect of alkyl groups on their biological activity. Mutagenicity of N-nitroso-N-alkylureas which spontaneously produce alkanediazohydroxides after non-enzymatic hydrolysis were also tested in comparison to that of the corresponding diazotates and other activated chemical species of N-nitrosamines. When the mutagenicity was assayed in three microbial strains, Salmonella typhimurium TA1535, and Escherichia coli WP2 and WP2 uvrA, the order of mutagenic potency of the compounds with the same alkyl group was as follows, (E)-diazotates > (Z)-diazotates > nitrosoureas. The effect of alkyl groups on the mutagenic potency was different in Salmonella strain and in E. coli strains, and this result could be explained by the efficiency of O6-alkylguanine-DNA alkyltransferase. In each bacterial strain, this effect of alkyl groups was similar in mutagenicity induced by (E)- and (Z)-diazotates, N-nitroso-N-alkylureas and other activated N-nitrosodialkylamines such as α-hydroxy nitrosamines. The geometrical isomerism affected the mutagenicity of (E)- and (Z)-potassium alkanediazotates, and the result suggested that alkanediazohydroxides react through diazonium ions in a cage rather than through free alkyldiazonium ions which have no geometrical isomerism. Our results confirmed that (E)-potassium alkanediazotates, (Z)-potassium alkanediazotates and N-nitroso-N-alkylureas all decomposed through diazohydroxides, and that alkanediazohydroxides are the active alkylating species of N-nitroso compounds, and also that the geometrical isomerism is important for carcinogenic N-nitroso compounds to show their biological activity.