98121-68-7Relevant academic research and scientific papers
A novel isocyanide-based three-component reaction: A facile synthesis of substituted 2H-pyran-3,4-dicarboxylates
Khalilzadeh, Mohammad A.,Hossaini, Zinatossadat,Baradarani, Mohammad M.,Hasannia, Adel
experimental part, p. 8464 - 8467 (2010/11/19)
An efficient method for synthesis of 2H-pyran-3,4-dicarboxylates using the three-component reaction of dithiocarbamates, dialkyl acetylenedicarboxylates, and isocyanides in solvent-free conditions is described. In these reactions, synthesis of dithiocarbamates is possibly based on the one-pot reaction of secondary amines, CS2, and alkyl halides in solvent-free conditions without using a catalyst. The mild reaction conditions and high yields of the reaction exhibit the good synthetic advantage of these methods.
