98131-22-7Relevant academic research and scientific papers
Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus
Gong, Wei,Zhang, Guofu,Liu, Tao,Giri, Ramesh,Yu, Jin-Quan
supporting information, p. 16940 - 16946 (2015/01/09)
Although the syntheses of novel and diverse peptides rely mainly on traditional coupling using unnatural amino acids, postsynthetic modification of peptides could provide a complementary method for the preparation of nonproteinogenic peptides. Site select
Efficient microwave-assisted synthesis of 4-amino-2-benzazepin-3-ones as conformationally restricted dipeptide mimetics
Severino, Beatrice,Fiorino, Ferdinando,Esposito, Antonella,Frecentese, Francesco,De Angelis, Francesca,Perissutti, Elisa,Caliendo, Giuseppe,Santagada, Vincenzo
experimental part, p. 206 - 211 (2009/04/07)
In this paper, we describe the synthesis of conformationally constrained dipeptide mimetic derivatives. Microwave flash heating was used in several synthetic steps providing the opportunity to perform the reactions in dramatically shortened time as well as to increase the obtained yields. The efficiency of the methodology makes it useful in order to prepare other dipeptides containing the 4-amino-tetrahydro-2-benzazepin-3-one motif.
