98203-48-6Relevant academic research and scientific papers
CHIRAL QUATERNARY CARBON COMPOUNDS. II. AN ASYMMETRIC SYNTHESIS OF (R) OR (S)-4,4-DIALKYL-2-CYCLOPENTENONES.
Meyers, A. I.,Wanner, Klaus Th.
, p. 2047 - 2050 (1985)
The chiral bicyclic lactam (5) derived from levulinic acid and (S)-valinol is sequentially alkylated and then cleaved to 2,2-dialkyl levulinaldehyde (8) which is cyclized to the title products (9) in > 99percent ee.
