Tetrahedron Letters p. 2047 - 2050 (1985)
Update date:2022-08-04
Topics:
Meyers, A. I.
Wanner, Klaus Th.
The chiral bicyclic lactam (5) derived from levulinic acid and (S)-valinol is sequentially alkylated and then cleaved to 2,2-dialkyl levulinaldehyde (8) which is cyclized to the title products (9) in > 99percent ee.
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Doi:10.1021/jm00151a002
(1986)Doi:10.1248/cpb.33.2287
(1985)Doi:10.1007/BF01518281
(1916)Doi:10.1016/S0040-4039(00)91596-X
(1992)Doi:10.1007/BF00807099
(1997)Doi:10.1002/hlca.19850680310
(1985)