98214-73-4

Upstream product

• 50-23-7 HYDROCORTISONE 

Downstream Products

• 103549-70-8 11β,17α,21-trihydroxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 17,21-ethyl orthopropanoate 
• 1258525-98-2 C₃₅H₃₇N₃O₃S₂ 
• 98214-72-3 11β-hydroxy-17α,21-dipropanoyloxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 
• 103549-71-9 11β-hydroxy-17α-butanoyloxy-21-chloro-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 
• 98214-71-2 11β,21-dihydroxy-17α-propanoyloxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 
• 98242-32-1 11β-hydroxy-21-chloro-17α-propanoyloxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 
• 98214-70-1 17α-acetoxy-11β,21-dihydroxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 
• 98214-74-5 11β,17α,21-trihydroxy-2'-phenyl-2'H-2,4-pregnadieno<3,2-c>pyrazol-20-one 17,21-ethyl orthoacetate 

Relevant academic research and scientific papers

Steroidal C-21 heteroaryl thioethers. Part 3: Pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids)

The introduction of A ring pyrazole modification to the hydrocortisone C-21 heteroaryl thioethers generated compounds with excellent transrepression potency (IL-8 inhibition) compared to their hydrocortisone analogs. However, the transcriptional transacti