98281-45-9Relevant academic research and scientific papers
Organocatalytic activation of TMSCN by basic ammonium salts for efficient cyanation of aldehydes and imines
Raj, I. Victor Paul,Suryavanshi, Gurunath,Sudalai
, p. 7211 - 7214 (2007)
Basic ammonium salts act as highly effective catalysts for the cyanosilylation of aldehydes and in Strecker-type aminonitrile synthesis using TMSCN as cyanide source at 25 °C under extremely mild conditions, affording very good to excellent yields of silylated cyanohydrins and α-aminonitriles.
Cu(OTf)2 or Et3N-catalyzed three-component condensation of aldehydes, amines and cyanides: a high yielding synthesis of α-aminonitriles
Paraskar, Abhimanyu S.,Sudalai, Arumugam
, p. 5759 - 5762 (2007/10/03)
Copper(II) triflate or Et3N have been found to catalyze, under ambient conditions, the addition of a cyanide anion, such as trimethylsilyl cyanide or acetone cyanohydrin, onto in situ generated imines, furnishing α-aminonitriles in excellent yi
