98305-75-0 Usage
Alias
AC-4
Chemical Class
Pyrimidine derivatives
Structural Feature
Contains a 4-chlorophenyl group attached to the 6-position of the pyrimidine ring
Therapeutic Applications
Anti-inflammatory: Investigated for its potential to reduce inflammation.
Anticancer: Studied for its possible role in cancer treatment.
Inhibition of Protein Kinase R (PKR): Explored for its ability to inhibit PKR, involved in immune and stress response regulation.
Targeted Diseases
Rheumatoid Arthritis: Investigated for potential therapeutic effects.
Ulcerative Colitis: Studied for potential treatment benefits.
Pharmacological Activities
Diverse: Exhibits various pharmacological activities.
Therapeutic Potential: Holds promise for therapeutic benefits in multiple medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 98305-75-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,3,0 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 98305-75:
(7*9)+(6*8)+(5*3)+(4*0)+(3*5)+(2*7)+(1*5)=160
160 % 10 = 0
So 98305-75-0 is a valid CAS Registry Number.
98305-75-0Relevant academic research and scientific papers
PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY
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Paragraph 0799; 0800; 0798, (2017/07/05)
A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis
Wyatt, Emma E.,Galloway, Warren R. J. D.,Thomas, Gemma L.,Welch, Martin,Loiseleur, Olivier,Plowright, Alleyn T.,Spring, David R.
supporting information; experimental part, p. 4962 - 4964 (2009/06/06)
The screening of a diversity-oriented synthesis library followed by structure-activity relationship investigations have led to the discovery of an anti-MRSA agent which operates as an inhibitor of Staphylococcus aureus dihydrofolate reductase. The Royal Society of Chemistry.
