98331-76-1

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 503169-76-4 1,1-bis(trifluoromethyl)-2-bromoethanol 
• 31898-68-7 2,2-bis(trifluoromethyl)oxirane 
• 829-85-6 diphenylphosphane 

Downstream Products

• 121288-88-8 NiH(P(C₆H₁₁)3)OC(CF₃)2CH₂P(C₆H₅)2 
• 121288-89-9 Ni⁽²⁺⁾*H^(1-)*2(P(C₆H₁₁)3)*(OC(CF₃)2CH₂P(C₆H₅)2)^(1-) 
• 106498-83-3 PtCl₂((C₆H₅)2PCH₂C(CF₃)2OH)2 
• 151925-28-9 Ni((C₆H₅)2PCH₂C(CF₃)2O)H((C₆H₅)2PCH₂C(CF₃)2OH) 
• 106436-03-7 PdCl₂((C₆H₅)2PCH₂C(CF₃)2OH)2 
• 106498-84-4 PtCl((C₆H₅)2PCH₂C(CF₃)2O)((C₆H₅)2PCH₂C(CF₃)2OH) 
• 106435-96-5 PtCl((C₆H₅)2PCH₂C(CF₃)2O)((C₆H₅)2PCH₂C(CF₃)2OH) 
• 98331-71-6 trans-bis(2-(diphenylphosphinomethyl)-1,1,1,3,3,3-hexafluoro-2-propanolate)nickel(II) 
• 106498-81-1 Pt((C₆H₅)2PCH₂C(CF₃)2O)2 
• 98331-75-0 bis(chloro)bis(2-(diphenylphoshinomethyl)-1,1,1,3,3,3-hexafluoro-2-propanolate)rhodium(III) 
• 98331-73-8 (2-(diphenylphosphinomethyl)-1,1,1,3,3,3-hexafluoro-2-propanolate)bis(P(C₆H₅)3)copper(I) 
• 105119-02-6 [(OC(CF₃)2CH₂P(C₆H₅)2)2Pd] 
• 98331-72-7 trans-bis(2-(diphenylphosphinomethyl)-1,1,1,3,3,3-hexafluoro-2-propanolate)cobalt(II) 
• 98331-74-9 bis-(2-(diphenylphoshineoxidemethyl)-1,1,1,3,3,3-hexafluoro-2-propanolate)copper(II) 

Relevant academic research and scientific papers

Facile preparation and synthetic applications of LiCH2C(CF3)2Oli

Bromohydrin BrCH2C(CF3)2OH readily reacts with two equivalents of n-BuLi at - 78 °C to produce the corresponding dilithium derivative LiCH2C(CF3)2OLi in high yield. This dilithiated derivative reacts selectively, acting as a C-nucleophile, with a variety of electrophiles such as R2PCl, carbonyl compounds, and epoxides, to give electron-deficient phosphines R2PCH2C(CF3)2OH, 1,3- and 1,4-diols, correspondingly.