98395-61-0

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[2-(4-nitrophenoxy)ethyl]-
• Synonyms: N-[2-(4-Nitro-phenoxy)-aethyl]-phthalimid;p-(2-phthalimidoethoxy)nitrobenzene;N-[2-(4-nitro-phenoxy)-ethyl]-phthalimide
• CAS NO: 98395-61-0
• Molecular Formula: C16H12N2O5
• Molecular Weight: 312.282
• Mol File: 98395-61-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(4-nitrophenoxy)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(4-nitrophenoxy)ethyl]-(98395-61-0)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[2-(4-nitrophenoxy)ethyl]-(98395-61-0)

Safety Data

• Hazardous Substances Data: 98395-61-0(Hazardous Substances Data)

Usage

Molecular Structure

The compound has a central isoindole ring with a 2-[2-(4-nitrophenoxy)ethyl]group attached to it.

Class

It belongs to the isoindole-1,3(2H)-dione class.

Nitro Compound

The compound contains a nitro group, making it a nitro compound.

Reactivity

The presence of the nitro group suggests potential reactivity.

Bioactivity

The presence of the nitro group also suggests potential bioactivity.

Applications

Nitro compounds are used in various fields such as pharmaceuticals, agrochemicals, and materials.

Interesting target for further research and development

Due to its reactivity and bioactivity, the compound is an interesting target for further research and development.

Upstream product

• 100-02-7 4-nitro-phenol 
• 3891-07-4 N-(2-Hydroxyethyl)phthalimide 
• 824-78-2 4-nitrophenol sodium salt 
• 16365-27-8 2-(4-nitrophenoxy)ethanol 
• 22483-44-9 4-nitrophenoxyethyl 4-toluenesulfonate 
• 1074-82-4 potassium phtalimide 
• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 1124-31-8 potassium 4-nitrophenolate 

Downstream Products

• 60814-16-6 4-Nitrophenyl 2-aminoethyl ether 
• 1965-54-4 N-(2-hydroxyethyl)-4-nitroaniline 
• 98395-62-1 1-amino-2-(4-nitrophenoxy)ethane hydrochloride 
• 101351-09-1 p-(2-phthalimidoethoxy)aniline 

Relevant articles and documents

Identification of N-(2-Phenoxyethyl)imidazo[1,2-a]pyridine-3-carboxamides as New Antituberculosis Agents

A series of imidazo[1,2-a]pyridine carboxamides (IPAs) bearing an N-(2-phenoxyethyl) moiety was designed and synthesized as new antitubercular agents. Seven 2,6-dimethyl IPAs demonstrated excellent in vitro activity (MIC: 0.025-0.054 μg/mL) against the drug susceptive H37Rv strain and two clinically isolated multidrug-resistant Mycobacterium tuberculosisstrains. Compound 10j displayed acceptable safety and pharmacokinetic properties, opening a new direction for further development.

Angiotensin II antagonizing compounds containing a 1,5-naphthyridine or a quinoline moiety

The invention concerns pharmaceutically useful novel compounds of the formula I, in which R1, R2, R3, R4, R5, X, X1 and Z have the various meanings defined herein, and their non-toxic salts

Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines

The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.