98395-61-0

Usage

Molecular Structure

The compound has a central isoindole ring with a 2-[2-(4-nitrophenoxy)ethyl]group attached to it.

Class

It belongs to the isoindole-1,3(2H)-dione class.

Nitro Compound

The compound contains a nitro group, making it a nitro compound.

Reactivity

The presence of the nitro group suggests potential reactivity.

Bioactivity

The presence of the nitro group also suggests potential bioactivity.

Applications

Nitro compounds are used in various fields such as pharmaceuticals, agrochemicals, and materials.

Interesting target for further research and development

Due to its reactivity and bioactivity, the compound is an interesting target for further research and development.

Upstream product

• 100-02-7 4-nitro-phenol 
• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 22483-44-9 4-nitrophenoxyethyl 4-toluenesulfonate 
• 1074-82-4 potassium phtalimide 
• 16365-27-8 2-(4-nitrophenoxy)ethanol 
• 3891-07-4 N-(2-Hydroxyethyl)phthalimide 
• 824-78-2 4-nitrophenol sodium salt 
• 1124-31-8 potassium 4-nitrophenolate 

Downstream Products

• 98395-62-1 1-amino-2-(4-nitrophenoxy)ethane hydrochloride 
• 60814-16-6 4-Nitrophenyl 2-aminoethyl ether 
• 1965-54-4 N-(2-hydroxyethyl)-4-nitroaniline 
• 101351-09-1 p-(2-phthalimidoethoxy)aniline 

Relevant academic research and scientific papers

Identification of N-(2-Phenoxyethyl)imidazo[1,2-a]pyridine-3-carboxamides as New Antituberculosis Agents

A series of imidazo[1,2-a]pyridine carboxamides (IPAs) bearing an N-(2-phenoxyethyl) moiety was designed and synthesized as new antitubercular agents. Seven 2,6-dimethyl IPAs demonstrated excellent in vitro activity (MIC: 0.025-0.054 μg/mL) against the drug susceptive H37Rv strain and two clinically isolated multidrug-resistant Mycobacterium tuberculosisstrains. Compound 10j displayed acceptable safety and pharmacokinetic properties, opening a new direction for further development.

LIQUID CRYSTAL ALIGNING AGENT

Provided is a liquid crystal aligning agent capable of forming a liquid crystal alignment film the surface of which is rarely scratched or abraded when rubbed, and which exhibits excellent liquid crystal aligning properties and enables the production of l

Angiotensin II antagonizing compounds containing a 1,5-naphthyridine or a quinoline moiety

The invention concerns pharmaceutically useful novel compounds of the formula I, in which R1, R2, R3, R4, R5, X, X1 and Z have the various meanings defined herein, and their non-toxic salts

INDOLE DERIVATIVES. 138. SYNTHESIS OF α-(5-INDOLYL)ETHYLAMINE AND 5-(2-AMINOETHOXY)- AND 5-(AMINOETHYLTHIO)TRYPTAMINES

The reaction of 5-acetylindole with hydroxylamine with subsequent reduction of the resulting oxime gave α-(5-indolyl)ethylamine.Coupling of 4-(2-phthalimidoethoxy)- and 4-(2-phthalimidoethylthio)phenyldiazonium chlorides with ethyl α-acetyl-δ-phthalimidov

Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines

The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.