98477-40-8Relevant articles and documents
COMPOUNDS AND USES THEREOF
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Page/Page column 120-121, (2020/10/20)
The present invention features compounds useful in the treatment of neurological disorders and primary brain cancer. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders and primary brain cancer.
Pyridinone diketo acids: inhibitors of HIV replication
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Page/Page column 13, (2008/06/13)
A new class of diketo acids constructed on pyridinone scaffolds, designed as inhibitors of HIV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS and ARC, either as the compounds, or as pharmaceutically acceptable salts, with pharmaceutically acceptable carriers, used alone or in combination with antivirals, immunomodulators, antibiotics, vaccines, and other therapeutic agents, especially other anti-HIV compounds (including other integrase-based anti-HIV agents). Methods of treating AIDS and ARC and methods of treating or preventing infection by HIV are also described.
THERMOLYSIS OF N-BENZYL DERIVATIVES OF 2-AMINOPYRIDINES. A CHARGE SENSITIVITY (CS) AND MNDO STUDY OF ELECTROPHILIC SUBSTITUTION OF 2-AMINOPYRIDINES
Kowalski, Piotr
, p. 97 - 108 (2007/10/02)
The thermolysis reaction of N-mono (1,2) and N-disubstituted (3,4) benzyl derivatives of 2-aminopyridines were carried out at 250 deg C in order to verify the scheme of the reaction of 2-aminopyridines with electrophiles.N-Annular benzyl substituent in 1