98515-98-1

Usage

Common Uses

Plasticizer in the production of plastics, resins, and other synthetic materials
Improves flexibility, durability, and stability of plastics
Used as a solvent and intermediate in organic synthesis

Chemical Structure

Diester of acetic acid and 1,2-cyclobutanedimethanol
Cisconfiguration

Industrial Applications

Wide range of products in the manufacturing industry

Safety Precautions

Should be handled with care

Physical Properties

Specific properties not provided in the material

Chemical Properties

Acts as a plasticizer, solvent, and intermediate in organic synthesis

Environmental Impact

Potential health and environmental risks if not handled properly

Regulatory Information

Specific regulatory information not provided in the material

Storage and Handling

Specific storage and handling instructions not provided in the material

Upstream product

• 4462-96-8 cis-1,2-cyclobutane dicarboxylic anhydride 
• 108-24-7 acetic anhydride 

Downstream Products

• 371784-53-1 ((1R,2R)-2-formylcyclobutyl)methyl acetate 
• 1883727-34-1 (1S,3'R,6'R,7'S,8'Z,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H,15'H-spiro[naphthalene-1,22'-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.0³'⁶.0¹⁹'²⁴]pentacosa[8,16,18,24]tetraen]-15'-one 13',13'-dioxide 
• 1883727-34-1 (1S,3’R,6’R,7’S,9’E,11’S,12’R)-6-chloro-7'-methoxy-11’,12’-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[9,16,18,24]tetraen]-15’-one-13’,13'-dioxide 

Relevant academic research and scientific papers

ALPHA-HYDROXY PHENYLACETIC ACID PHARMACOPHORE OR BIOISOSTERE MCL-1 PROTEIN ANTAGONISTS

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (I), or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.

TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, (I) and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.