98545-15-4

Usage

Uses

Used in Pharmaceutical Synthesis:
1-Piperazineethanamine,N,4-dimethyl-(9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to form stable bonds with other molecules, making it a valuable component in the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 1-Piperazineethanamine,N,4-dimethyl-(9CI) is used as a building block for the creation of various agrochemicals. Its ability to form stable compounds makes it suitable for use in the development of effective and safe pesticides and other agricultural products.
Used in Corrosion Inhibitor Manufacturing:
1-Piperazineethanamine,N,4-dimethyl-(9CI) is used as a corrosion inhibitor in various industrial applications. Its chemical properties enable it to form protective layers on metal surfaces, preventing corrosion and extending the life of equipment and structures.
Used in Photoinitiator Production:
In the field of photoinitiators, 1-Piperazineethanamine,N,4-dimethyl-(9CI) is used as a key component in the production of materials that initiate chemical reactions upon exposure to light. Its ability to absorb light and generate reactive species makes it an essential ingredient in the formulation of photoinitiators for various applications, such as coatings, inks, and adhesives.

InChI:InChI=1/C8H19N3/c1-9-3-4-11-7-5-10(2)6-8-11/h9H,3-8H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 817-09-4 tris-(2-chloroethyl)amine hydrochloride 
• 74-89-5 methylamine 
• 69793-59-5 N-[2-(4-formylpiperazin-1-yl)ethyl]formamide 
• 140-31-8 aminoethylpiperazine 
• 1211464-81-1 C₁₀H₂₁N₃O₂ 
• 1291568-85-8 N-methyl-2-piperazin-1-ylethanamine 

Downstream Products

• 1421372-74-8 N-(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)-2-methoxy-N'-methyl-N'-[2-(4-methylpiperazin-1-yl)ethyl]-5-nitrobenzene-1,4-diamine 
• 1421372-73-7 N⁴-(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)-5-methoxy-N¹-methyl-N¹-[2-(4-methylpiperazin-1-yl)ethyl]benzene-1,2,4-triamine 
• 1421373-70-7 N-(5-((5-chloro-4-(pyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl)amino)-4-methoxy-2-(methyl(2-(4-methylpiperazin-1-yl)ethyl)amino)phenyl)acrylamide 

Relevant academic research and scientific papers

2 - (2, 4, 5 - SUBSTITUTED -ANILINO) PYRIMIDINE DERIVATIVES AS EGFR MODULATORS USEFUL FOR TREATING CANCER

The present invention relates to certain 2-(2,4,5-substituted-anilino) pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant). Such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers. The invention also relates to pharmaceutical compositions comprising said compounds and salts thereof, especially useful polymorphic forms of these compounds and salts, intermediates useful in the manufacture of said compounds and to methods of treatment of diseases mediated by various different forms of EGFR using said compounds and salts thereof.

Asymmetric synthesis catalyzed by chiral ferrocenylphosphine transition metal complexes. 10 gold(I)-catalyzed asymmetric aldol reaction of isocyanoacetate

Optically active ferrocenylbisphosphine ligands containing 2-(dialkylamino)ethylamino group on the ferrocenylmethyl position have been prepared and used for the gold(I)-catalyzed asymmetric aldol reaction of isocyanoacetate with aldehydes. Six-membered ring amines, such as morpholino or piperidino group, at the terminal of the side chain were most stereoselective to give optically active trans-4- methoxycarbonyl-5-alkyl-2-oxazolines (up to 97% ee) with high enantio- and diastereoselectivity in a quantitative yield.