98567-06-7

Upstream product

• 23132-67-4 2-methyl-4-amino-6-methoxypyrimidine 
• 29634-62-6 3-bromo-1-phenylpropane-1,2-dione 
• 144-55-8 sodium hydrogencarbonate 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 93-55-0 1-phenyl-propan-1-one 

Relevant academic research and scientific papers

Synthesis of (Imidazopyrimidin-2-yl)phenylmethanones and 6-Benzoylpyrrolopyrimidinones

4-Pyrimidinamines have been reacted with 3-bromo-1-phenylpropane-1,2-dione to give a series of (imidazopyrimidin-2-yl)phenylmethanones.The dione also reacted with ethyl amidinoacetate to yield ethyl 2-amino-5-benzoylpyrrole-2-carboxylate which was used to prepare a series of 6-benzoylpyrrolopyrimidines.

2-substituted imidazo[1,2-c]pyrimidines having anxiolytic properties

Novel imidazo[1,2-c]pyrimidines of the formula STR1 wherein R is an aryl of 6 to 12 carbon atoms, R 1 is selected from the group consisting of hydrogen and alkyl, alkoxy and alkylthio of 1 to 5 carbon atoms when R 2 and R 3 together form a carbon-nitrogen bond or R 1 and R 2 together are 0 when R 3 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and alkenyl of 2 to 5 carbon atoms, R 4 is selected from the group consisting of alkoxy and alkylthio of 1 to 5 carbon atoms, R 5 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having anxiolytic properties.