98695-13-7

Upstream product

• 67-56-1 methanol 
• 20806-43-3 Z-Ser(Bzl)-OH 
• 186581-53-3 diazomethane 
• 20806-39-7 N-(benzyloxycarbonyl)-O-benzylserine 
• 22831-98-7 4-benzyloxymethyl-oxazolidine-2,5-dione 
• 5445-44-3 O-benzylserine 
• 394210-41-4 4-benzyloxymethyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 1379661-54-7 (S)-3-(benzyloxy)-2-(benzyloxycarbonylamino)propyl 4-methylbenzenesulfonate 
• 1379661-55-8 (R)-benzyl 1-(benzyloxy)-3-(piperidin-1-yl)propan-2-ylcarbamate 
• 58578-42-0 (R)-benzyl 1-(benzyloxy)-3-hydroxypropan-2-ylcarbamate 
• 20806-43-3 Z-Ser(Bzl)-OH 
• 20806-42-2 (R)-N-benzyloxycarbonyl-O-benzyl serine 
• 172745-74-3 R,S-1-O-Benzyl-2-(benzyloxycarbonylamino)-1,3-propandiol 
• 98695-17-1 N-[1-benzyloxy-3-oxopropan-2-yl]carbamic acid benzyl ester 
• 46460-82-6 O-benzyl-L-serine methyl ester 

Relevant academic research and scientific papers

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines catalyzed by a leucine-derived bifunctional catalyst

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines were developed using a bifunctional catalyst readily prepared from l-leucine. The chiral benzylic amine products were obtained in high yields (up to 96% yield) and good to high enantiomeric excesses (up to 95% ee).

Note on the Preparation of N-substituted Aminoglyceraldehydes

O-Benzyl-N-(benzyloxycarbonyl)-DL-serine methyl ester (1a) and peptides 1b-d with C-terminal O-benzylserine ester have been reduced with diisobutylaluminium hydride to yield the N-substituted aminoglyceraldehydes 2a-d.Using lithium tetrahydridoaluminate as the reducing agent the corresponding alcohols 3a-d have been obtained. - (Keywords: Maillard reaction; N-Substituted aminoglyceraldehydes)