98733-24-5

Basic information

• Product Name: 3,4-O-ISOPROPYLIDENE-L-THREONIC ACID, CALCIUM SALT
• Synonyms: 3,4-O-ISOPROPYLIDENE-L-THREONIC ACID, CALCIUM SALT
• CAS NO: 98733-24-5
• Molecular Formula: 2C₇H₁₁O₅*Ca
• Molecular Weight: 390.4
• Product Categories: Carbohydrate Synthesis;Monosaccharides;Specialty Synthesis
• Mol File: 98733-24-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: /
• BRN: 5670587
• CAS DataBase Reference: 3,4-O-ISOPROPYLIDENE-L-THREONIC ACID, CALCIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-O-ISOPROPYLIDENE-L-THREONIC ACID, CALCIUM SALT(98733-24-5)
• EPA Substance Registry System: 3,4-O-ISOPROPYLIDENE-L-THREONIC ACID, CALCIUM SALT(98733-24-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 98733-24-5(Hazardous Substances Data)

Usage

InChI:InChI=1/2C7H12O5.Ca/c2*1-7(2)11-3-4(12-7)5(8)6(9)10;/h2*4-5,8H,3H2,1-2H3,(H,9,10);/q;;+2/p-2/t2*4-,5+;/m00./s1

Upstream product

• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 7440-44-0 pyrographite 
• 7440-05-3 palladium 

Downstream Products

• 1301239-46-2 {[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methylene}-1,1-diphenylmethanamine 
• 1301239-48-4 (3S,4S)-3-acetyl-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)azetidin-2-one 
• 1017251-76-1 (3S,4S)-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-3-[(1S)-1-hydroxyethyl]azetidin-2-one 
• 1301239-59-7 (3S,4S)-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-3-[(1R)-1-hydroxyethyl]azetidin-2-one 
• 1301239-61-1 (1R)-1-[(2S,3S)-2-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-4-oxoazetidin-3-yl]ethyl benzoate 
• 1301239-63-3 (1S)-1-[(2S,3S)-2-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-4-oxoazetidin-3-yl]ethyl methanesulfonate 
• 1301239-67-7 (3E,4S)-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-3-ethylideneazetidin-2-one 
• 1301239-69-9 (3Z,4S)-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-3-ethylideneazetidin-2-one 
• 1301239-65-5 (1R)-1-[(2S,3S)-2-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(diphenylmethyl)-4-oxoazetidin-3-yl]ethyl acetate 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 36326-38-2 ethyl (E)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 
• 92973-40-5 methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF [(1 S,2R)-3-[[(4-AMINOPHENYL)SULFONYL] (2-METHYLPROPYL)AMINO]-2-HYDROXY-1 -(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM

The present invention relates to an improved process for the preparation of [(1 S,2R)-3-[ [(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy- 1 -(phenylmethyl)propyl] - carbamic acid (3R,3aS,6aR)hexahydrofuro[2,3-b]furan-3-yl ester compound of formula- 1 represented by the following structural formula:

1,4-Dioxane-2,5-dione-type monomers derived from l-ascorbic and d-isoascorbic acids. Synthesis and polymerisation

l-Ascorbic and d-isoascorbic acids have been used as the starting materials for the preparation of (3R,4′S)-3-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)-1,4-dioxane-2,5-dione (IPTA), (3R and S, 4′S,6R)-3-methyl-6-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)-1,4-dioxane-2,5-dione (IPTP) and (3R,4′R)-3-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)-1,4-dioxane-2,5-dione (IPEA), three novel 1,4-dioxane-2,5-dione-type monomers. Ring-opening homopolymerisation and copolymerisation of the IPTA monomer, derived from l-ascorbic acid, with d,l-lactide have been performed. The polymers were characterised by elemental microanalysis, as well as IR and 1H and 13C NMR spectroscopies. GPC was used to estimate product molecular weights, and thermal studies (DSC and TGA) revealed that all the polymers were amorphous, being stable up to 250 °C under nitrogen.

Synthesis of chiral β-lactams using L-ascorbic acid

-