98815-42-0Relevant articles and documents
The use of K-10/ultrasound in the selective synthesis of unsymmetrical β-enamino ketones
Valduga, Claudete J.,Squizani, Adriana,Braibante, Hugo S.,Braibante, Mara E.F.
, p. 1019 - 1022 (2007/10/03)
p-Phenyl substituted β-enamino ketones 2a-p and cyclic β-enamino ketones 4, 6a-f have been prepared by a selective method by dispersing 1,3- diketones and amines on montmorillonite K-10 under sonication.
Metal-carbonyl-Induced Reaction of Isoxazoles. Ring Cleavage and Reduction by Hexacarbonylmolybdenum, Pentacarbonyliron, or Nonacarbonyldi-iron
Nitta, Makoto,Kobayashi, Tomoshige
, p. 1401 - 1406 (2007/10/02)
In the presence of and water the isoxazoles (1a-f) undergo thermally induced reductive cleavage of the N-O bond to give β-amino enones in good yield.Similar results were obtained by the use of and water with photoirradiation, or of and water with heating.A mechanism involving an N-complexed isoxazolepentacarbonylmolybdenum or isoxazoletetracarbonyliron, and a - or -complexed (β-oxo vinyl)nitrene intermediate is proposed for the reactions.The complexed nitrene moiety could be reduced by the central metal in the presence of water to give amine.Furthermore, treatment of 2-benzoyl- 3-phenyl-2-H-azirine (8a), which is an isomer of 3,5-diphenylisoxazole, with the metal carbonyls and water also resulted in the formation of a β-amino enone possibly via the corresponding complexed (β-oxo vinyl)nitrene.An N-complexed isoxazole-pentacarbonylmolybdenum intermediate was prepared by the photoreaction of with 3,5-dimethylisoxazole.Its characterization, and chemical transformations, have been carried out to investigate the proposed mechanism.
