98830-20-7

Basic information

• Product Name: 25-hydroxydihydrotachysterol(2)
• Synonyms: 25-hydroxydihydrotachysterol(2)
• CAS NO: 98830-20-7
• Molecular Formula: C₂₈H₄₆O₂
• Molecular Weight: 414.66364
• Mol File: 98830-20-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 537°Cat760mmHg
• Flash Point: 222.1°C
• Appearance: /
• Density: 1.051g/cm³
• Vapor Pressure: 8.99E-14mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 25-hydroxydihydrotachysterol(2)(CAS DataBase Reference)
• NIST Chemistry Reference: 25-hydroxydihydrotachysterol(2)(98830-20-7)
• EPA Substance Registry System: 25-hydroxydihydrotachysterol(2)(98830-20-7)

Safety Data

• Hazardous Substances Data: 98830-20-7(Hazardous Substances Data)

Usage

General Description

25-hydroxydihydrotachysterol(2) is a synthetic form of vitamin D that is used as a therapeutic agent for the treatment of hypocalcemic conditions such as hypoparathyroidism and pseudo-hypoparathyroidism. It works by increasing the absorption of calcium and phosphorus in the intestines, as well as promoting the reabsorption of calcium in the kidneys. This helps to maintain proper levels of these minerals in the body, which are essential for bone health and overall bodily function. However, this chemical should be used with caution, as excessive levels of vitamin D can lead to hypercalcemia, which can have detrimental effects on health.

InChI:InChI=1/C28H46O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,19-21,24-26,29-30H,7-8,10,14-18H2,1-6H3/b11-9+,22-12+,23-13+/t19-,20+,21-,24-,25+,26-,28+/m0/s1

Upstream product

• 142980-90-3 ethyl <(1'R,2'S,5'S)-5'-<(tert-butyldimethylsilyl)oxy>-1'-hydroxy-2'-methylcyclohexyl>ethanoate 
• 142980-88-9 ethyl <(1'R,2'S,5'S)-5'-acetoxy-1'-hydroxy-2'-methylcyclohexyl>ethanoate 
• 142980-87-8 ethyl <(1'R,2'S,5'S)-6-hydroperoxy-2',6-'dimethylbicyclo<3.2.1>-7'-oxaoctyl>ethanoate 
• 142980-89-0 ethyl <(1'R,2'S,5'S)-1',5-'dihydroxy-2'-methylcyclohexyl>ethanoate 
• 141277-81-8 (2E)-<2-<(2'S,5'S)-5'-<(tert-butyldimethylsilyl)oxy>-2'-methylcyclohexylidene>ethyl>diphenylphosphine oxide 
• 100858-24-0 (22E,24S)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>ergost-22-ene 
• 100858-25-1 (22E,24S)-de-A,B-25-[(methoxymethyl)oxy]ergost-22-en-8β-ol 
• 142980-91-4 (2E)-ethyl <(2'S,5'S)-5'-<(tert-butyldimethylsilyl)oxy>-2'-methylcyclohexylidene>ethanoate 
• 142980-82-3 (2E)-ethyl <(2'S,5'S)-2'-methyl-5'-(1''-methylethenyl)cyclohexylidene>ethanoate 
• 142980-92-5 (2E)-2-<(2'S,5'S)-5'-<(tert-butyldimethylsilyl)oxy>-2'-methylcyclohexylidene>ethanol 
• 145260-95-3 [(2S,5S)-5-Hydroxy-2-methyl-cyclohex-(E)-ylidene]-acetic acid ethyl ester 
• 138079-57-9 Benzoic acid (1R,3aR,4S,7aR)-1-((E)-(1R,4S)-5-hydroxy-1,4,5-trimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-yl ester 
• 64190-52-9 (8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol 
• 5524-05-0 (-)-dihydrocarvone 

Relevant articles and documents

A Convergent Approach to the Dihydrotachysterol Diene System. Application to the Synthesis of Dihydrotachysterol2 (DHT2), 25-Hydroxydihydrotachysterol2 (25-OH-DHT2), 10(R),19-dihydro-(5E)-3-epivitamin D2, and 25-Hydroxy-10(R),19-dihydro-(5E)-3-epivitamin D2

Total synthesis of A-ring fragments of 10(S),19-dihydrovitamins D and 10(R),19-dihydro-(5E)-epivitamins D from (+)-(S)-carvone and (-)-(R)-carvone is described.These fragments were used for convergent synthesis of dihydrotachysterol2 (DHT2), 25-hydroxydihydrotachysterol2, 10(R),19-dihydro-(5E)-3-epivitamin D2, and 25-hydroxy-10(R),19-dihydro-(5E)-3-epivitamin D2.