100858-24-0Relevant articles and documents
25-Hydroxydihydrotachysterol2. An innovative synthesis of a key metabolite of dihydrotachysterol2
Hanekamp,Rookhuizen,Bos,Brandsma
, p. 9283 - 9294 (2007/10/02)
A new synthesis of 25-hydroxydihydrotachysterol2 is described. The hydroxylated side-chain is constructed stereoselectively using a chiral Wittig reagent. The A-ring synthon is introduced utilising the Wittig-Horner method as developed by Lythgoe et al. The preparation of the metabolite is carried out in 18 steps.