98832-58-7

Upstream product

• 64842-92-8 2-Nitro-6,7,8,9-tetrahydro-11H-pyrido<2,1-b>quinazolin-11-one 
• 98-88-4 benzoyl chloride 
• 70934-09-7 2-amino-6,7,8,9-tetrahydro-11Hpyrido[2,1-b]quinazolin-11-one 
• 2446-62-0 7,8,9-trihydropyrido[2,1-b]quinazolin-11(6H)-one 

Downstream Products

• 1446320-26-8 8-benzoylamino-4-(3,4-dimethoxybenzylidene)mackinazolinone 
• 1446320-27-9 8-benzoylamino-4-(furfurylidene-2)mackinazolinone 
• 1446320-22-4 8-benzoylamino-4-benzylidenemackinazolinone 
• 1446320-23-5 8-benzoylamino-4-(4-hydroxybenzylidene)mackinazolinone 
• 1446320-24-6 8-benzoylamino-4-(4-dimethylaminobenzylidene)mackinazolinone 
• 1446320-25-7 8-benzoylamino-4-(4-nitrobenzylidene)mackinazolinone 

Relevant academic research and scientific papers

Synthesis of 8-amino- and 8-acetyl(benzoyl) aminomackinazolinones and their condensation with aldehydes

Methods for preparing of 8-nitro- and 8-aminomackinazolinones were improved. 8-Acetyl(benzoyl)aminomackinazolinones reacted smoothly with aromatic aldehydes and furfurol in glacial acetic acid to give the corresponding 4-arylidene-substituted derivatives. Reaction of 8-aminomackinazolinone with aromatic aldehydes in glacial acetic acid was accompanied by acetylation of the amine and gave 8-acetylamino-4-arylidenemackinazolinones. Reaction of 8-aminomackinazolinone and p-nitrobenzaldehyde in propionic acid produced 8-[(4' -nitrobenzylidene)amino]-4-(4'-nitrobenzylidene)mackinazolinone. In contrast, the reaction in Py occurred selectively at the amine to form the corresponding Schiff base 8-[(4'-nitrobenzylidene)amino]mackinazolinone.