98891-40-8

Upstream product

• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 29877-76-7 4-methoxy-2-methylthio-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 197845-32-2 7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-4-methoxy-2-methylthio-5-(1-morpholinomethyl)-7H-pyrrolo[2,3-d]pyrimidine 
• 197845-33-3 7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-2-methylthio-5-(1-morpholinomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidine-4-one 

Relevant academic research and scientific papers

7-Deaza-2'-deoxyinosine: A stable nucleoside with the ambiguous base pairing properties of 2'-deoxyinosine

The base pairing ambiguity of 7-deaza-2'-deoxyinosine (c7I(d), 2) was studied and was found to be the same as that of 2'-deoxyinosine. The duplex stability decreases in the order [d(c7I-C) > d(c7I-A) > d(c7I-T)

Regioselectivity of the Mannich reaction on pyrrolo[2,3-d]pyrimidine nucleosides related to 7-deaza-2'-deoxyadenosine or 7-deaza-2'-deoxyguanosine

Mannich reactions were performed on 7-deazapurine 2'-deoxyribonucleosides and the regioselectivity was studied. 7-Deaza-2'-deoxy-adenosine (2'-deoxytubercidin, 4a) furnished the 7-substituted Mannich base 5a. The side chain was introduced in the 8-positio

Synthesis of 7-Deaza-2'-deoxyinosine by Phase-Transfer Glycosylation

Phase-transfer glycosylation of the pyrrolopyrimidine 3a with the 2'-deoxy halogenose 5 leads in a regio- and diastereoselektive reaction to compound 6a.The latter was converted into the nucleoside 6b by removal of the protecting groups.Nucleophili