98926-55-7 Usage
Molecular Structure
2-(3-chlorobenzamino)propanoic acid ethyl ester consists of a propanoic acid moiety with an ethyl ester group and a 3-chlorobenzamino group attached to the second carbon of the chain.
Functional Groups
Contains a carboxyl group (-COOH), an amino group (-NH2), and an ethyl ester group (-OCH2CH3).
Aromatic Ring
The presence of a chlorinated benzene ring provides the molecule with aromaticity and stability.
Physical Properties
The physical properties of 2-(3-chlorobenzamino)propanoic acid ethyl ester include its molecular weight, melting point, boiling point, and solubility in various solvents.
Chemical Reactivity
The presence of the carboxyl and amino groups makes the molecule capable of undergoing various chemical reactions, such as esterification, amidation, and acylation.
Uses
2-(3-chlorobenzamino)propanoic acid ethyl ester is commonly used in pharmaceutical and agrochemical research as a building block in the synthesis of various active pharmaceutical ingredients and agricultural chemicals. It can also act as a substrate or intermediate in organic reactions and has potential applications in the chemical and pharmaceutical industries.
Versatility
The unique structure and properties of 2-(3-chlorobenzamino)propanoic acid ethyl ester make it a versatile compound with a wide range of potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 98926-55-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,9,2 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 98926-55:
(7*9)+(6*8)+(5*9)+(4*2)+(3*6)+(2*5)+(1*5)=197
197 % 10 = 7
So 98926-55-7 is a valid CAS Registry Number.
98926-55-7Relevant academic research and scientific papers
Effect of modifications of the alkylpiperazine moiety of trazodone on 5HT(2A) and α1 receptor binding affinity
Giannangeli, Marilena,Cazzolla, Nicola,Luparini, Maria Rita,Magnani, Maurizio,Mabilia, Massimo,Picconi, Giuseppe,Tomaselli, Mauro,Baiocchi, Leandro
, p. 336 - 345 (2007/10/03)
A series of triazolopyridine derivatives (compounds 2a-1) were synthesized in order to explore the effect of modifications of the alkylpiperazine moiety of trazodone (fragment A) on binding affinity for 5HT(2A) and α1 receptors. All of the synthesized compounds show a decrease of affinity for both 5HT(2A) and α1 receptors, as compared to trazodone, with the exception of compounds 2b,c which bear a methyl group in an α position to the aliphatic nitrogen atom N1. These compounds showed a decrease of affinity only for the α1 receptor. The stereochemical influence of the piperazine moiety of compound 2c was also evaluated. Enantiomer (S)- 2c showed the most significant differences between 5HT(2A) and α1 receptor affinity (IC50 values) and among the corresponding functional properties (pA2 values). Since (S)-2c cannot generate the metabolite 4-(3- chlorophenyl)piperazine this product was selected for further pharmacological studies.
