β-Phenoxy-isobutyronitrile, also known as β-phenyloxyisobutyronitrile or PBO, is an organic compound with the chemical formula C10H9NO. It is a colorless to pale yellow liquid with a molecular weight of 159.19 g/mol. PBO is a potent and selective inhibitor of the enzyme monoamine oxidase-B (MAO-B), which is involved in the metabolism of neurotransmitters such as dopamine, serotonin, and norepinephrine. This inhibition can lead to increased levels of these neurotransmitters in the brain, which may have potential therapeutic applications in the treatment of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. PBO is also used as a research tool to study the role of MAO-B in various biological processes. It is important to note that PBO is not approved for clinical use and requires further research to determine its safety and efficacy in humans.
99059-96-8
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Basic information
- Product Name: β-phenoxy-isobutyronitrile
- Synonyms:
- CAS NO:99059-96-8
- Molecular Formula:
- Molecular Weight: 161.203
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: β-phenoxy-isobutyronitrile(CAS DataBase Reference)
- NIST Chemistry Reference: β-phenoxy-isobutyronitrile(99059-96-8)
- EPA Substance Registry System: β-phenoxy-isobutyronitrile(99059-96-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 99059-96-8(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 99059-96-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,0,5 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.Calculate Digit Verification of CAS Registry Number 99059-96:
(7*9)+(6*9)+(5*0)+(4*5)+(3*9)+(2*9)+(1*6)=188
188 % 10 = 8
So 99059-96-8 is a valid CAS Registry Number.
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β-phenoxy-isobutyronitrile
