99065-34-6

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 1-(AMINOMETHYL)CYCLOPENTANECARBOXYLATE is used as an intermediate in the manufacturing of pharmaceuticals for its ability to contribute to the development of drugs with analgesic and anti-inflammatory properties. Its role in drug synthesis is crucial for creating medications that can alleviate pain and reduce inflammation, addressing a wide range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 1-(AMINOMETHYL)CYCLOPENTANECARBOXYLATE is employed as an intermediate in the production of agrochemicals. Its application is vital for the synthesis of compounds that can protect crops from pests and diseases, thereby ensuring agricultural productivity and food security.
Used as a Building Block in Organic Chemistry:
ETHYL 1-(AMINOMETHYL)CYCLOPENTANECARBOXYLATE is utilized as a building block in organic chemistry reactions. Its structural properties make it a valuable component in the synthesis of complex organic molecules, contributing to the advancement of chemical research and the development of new materials and compounds with diverse applications.

Upstream product

• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 
• 105-56-6 ethyl 2-cyanoacetate 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 

Downstream Products

• 204514-22-7 1-(<<(tert-butoxy)carbonyl>amino>methyl)cyclopentane-1-carboxylic acid 
• 137864-26-7 ethyl N-[(2'-cyanobiphenyl-4-yl)methyl]-1-aminomethylcyclopentane-1-carboxylate 

Relevant academic research and scientific papers

The design and synthesis of potent cyclic peptide VCAM-VLA-4 antagonists incorporating an achiral Asp-Pro mimetic

The Asp-Pro sequence of the cyclic peptide Ac-HN-Tyr-Cys*-Asp-Pro-Cys*-OH (1) could be replaced with the achiral dipeptide mimetic 1-(2-aminoethyl)cyclpentylcarboxylic acid with retention of potent inhibition of the VCAM-VLA-4 interaction. (C) Elsevier Science Ltd. All rights reserved.

N-ACYL-N-QUINOLINYL OR ISOQUINOUNYL ALKYLAMINO ACIDS COMPOSITIONS AND METHOD OF USE

The invention relates to N-acyl-N-heterocyclylalkylamino acids of the formula STR1 The compounds and their pharmaceutically acceptable salts can be used as antihypertensives, agents for the treatment of glaucoma, or for increasing the flow of the retinal

ACYL COMPOUNDS

Compounds of the formula STR1 in which R 1 is an aliphatic hydrocarbon radical which is unsubstituted or substituted by halogen or hydroxyl, or a cycloaliphatic or araliphatic hydrocarbon radical; X 1 is CO, SO 2, or--O--C(=O)--with the carbon atom of the carbonyl group being attached to the nitrogen atom shown in formula I; X 2 is a divalent aliphatic hydrocarbon radical which is unsubstituted or substituted by hydroxyl, carboxyl, amino, guanidino or a cycloaliphatic or aromatic radical, or is a divalent cycloaliphatic hydrocarbon radical, it being possible for a carbon atom of the aliphatic hydrocarbon radical to be additionally bridged by a divalent aliphatic hydrocarbon radical; R. sub.2 is carboxyl which, if desired, is esterified or amidated, substituted or unsubstituted amino, formyl which, if desired, is acetalized, 1H-tetrazol-5-yl, pyridyl, hydroxyl which, if desired, is etherified, S(O) m--R where m is 0, 1 or 2 and R is hydrogen or an aliphatic hydrocarbon radical, alkanoyl, unsubstituted or N-substituted sulfamoyl or PO n H 2 where n is 2 or 3; X 3 is a divalent aliphatic hydrocarbon; R 3 is carboxyl, 5-tetrazolyl, SO. sub.3 H, PO. sub.2 H 2, PO 3 H 2 or haloalkylsulfamoyl; and the rings A and B independently of one another are substituted or unsubstituted; in free form or in salt form, can be prepared in a manner known per se and can be used, for example, as medicament active ingredients.

N-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS IN WHICH THEY ARE PRESENT

The invention relates to N-substituted heterocyclic derivatives and its salts. These derivatives have the formula (I) in which the substituents are as defined in the specification. Application: Angiotensin II antagonists