99092-03-2

Basic information

• Product Name: Cyclopentanecarboxylic acid, 1-(aminomethyl)-, methyl ester
• Synonyms: Cyclopentanecarboxylic acid, 1-(aminomethyl)-, methyl ester
• CAS NO: 99092-03-2
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.21
• Mol File: 99092-03-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 1-(aminomethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 1-(aminomethyl)-, methyl ester(99092-03-2)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 1-(aminomethyl)-, methyl ester(99092-03-2)

Safety Data

• Hazardous Substances Data: 99092-03-2(Hazardous Substances Data)

Upstream product

• 40862-12-2 methyl 1-cyanocyclopentanecarboxylate 
• 40195-25-3 [cyclopentylidene(methoxy)methoxy](trimethyl)silane 
• 94143-87-0 1-(1,1,1,3,3,3-Hexamethyl-disilazan-2-ylmethyl)-cyclopentanecarboxylic acid methyl ester 

Downstream Products

• 204514-22-7 1-(<<(tert-butoxy)carbonyl>amino>methyl)cyclopentane-1-carboxylic acid 
• 102074-43-1 1-(aminomethyl)cyclopentane carboxylic acid 

Relevant articles and documents

Substituted cycloalkyls as inhibitors of a beta protein production

This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of Aβ-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to β-amyloid production such as Alzheimer's disease and Down's Syndrome.

N,N-Bis(trimethylsilyl)methoxymethylamine as a Convenient Synthetic Equivalent for +CH2NH2: Primary Aminomethylation of Esters

The introduction of a primary aminomethyl unit at the α position of esters can be achieved in high yield by the silyl trifluoromethanesulphonate-catalysed reaction of ketene silyl acetals (2) with N,N-bis(trimethylsilyl)methoxymethylamine (1).