99149-83-4Relevant articles and documents
Method for preparing perindopril despinner and intermediate thereof
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Paragraph 0038; 0057-0059, (2018/11/22)
The invention discloses a method for preparing perindopril despinner and an intermediate thereof. The method comprises the following steps: halogenating N-propionyl indole-2-carboxylic acid under theaction of a halogenation reagent so as to obtain a halogenation product, and further carrying out amine substitution and catalytic hydrogenation reduction on the obtained halogenation product, therebyobtaining the perindopril despinner. Compared with the prior art, the method is cheap and easy in reaction raw material, has a total yield as high as 64%, is high in product purity and is applicableto industrial production.
PROCESS FOR THE PREPARATION OF THE L-ARGININE SALT OF PERINDOPRIL
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Paragraph 0047, (2013/07/19)
Process for the preparation of the compound of formula (I):
SALTS OF PERINDOPRIL
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Page/Page column 15-16, (2009/03/07)
The present invention relates to new salts of perindopril, particularly to a new calcium salt and new amine salts of perindopril, to a process for their preparation and to a pharmaceutical formulations containing the new salts.