99192-09-3Relevant articles and documents
Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids
La Spisa, Fabio,Tron, Gian Cesare
supporting information, p. 7060 - 7063 (2015/01/08)
A sequential multicomponent synthesis among acyl chlorides, isocyanides, and silver salts of carboxylic acids was developed to synthesize α-ketoimides. The latter undergo an intramolecular aza-Wittig reaction to afford 2-acylquinazolinones.
A remarkable one-pot sequential four-component synthesis of tetrahydroquinazolines via an isocyanide-based multicomponent reaction
Shaabani, Ahmad,Mahyari, Mojtaba,Aghaei, Morteza,Keshipour, Sajjad,Ng, Seik Weng
, p. 1968 - 1972 (2013/09/24)
A novel one-pot sequential four-component strategy has been developed for the synthesis of tetrahydroquinazolines using either an aliphatic or an acyl halide, an isocyanide, and a 1,3-diamine, in methanol at 60 °C, in good to moderate yields without using a catalyst. Georg Thieme Verlag Stuttgart, New York.
