99214-52-5

Usage

Uses

Used in Coordination Chemistry:
4,7-Diaza-spiro[2.5]octane is utilized as a ligand in coordination chemistry, where it plays a crucial role in metal catalysis and organic synthesis. Its unique structure allows it to form stable complexes with metal ions, enhancing the efficiency and selectivity of catalytic reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4,7-Diaza-spiro[2.5]octane serves as a valuable building block for the development of various drugs. Its ability to form stable complexes with metal ions makes it a promising candidate for the design of novel pharmaceutical agents with improved therapeutic properties.
Used in Agrochemical Industry:
Similarly, in agrochemicals, 4,7-Diaza-spiro[2.5]octane is employed as a key component in the synthesis of pesticides and other agrochemicals. Its unique structure and coordination capabilities contribute to the development of more effective and environmentally friendly agrochemical products.

InChI:InChI=1/C6H12N2/c1-2-6(1)5-7-3-4-8-6/h7-8H,1-5H2

Upstream product

• 129306-17-8 4,7-diazaspiro[2.5]octane-5,8-dione 
• 1222106-45-7 7-benzyl-4,7-diazaspiro[2.5]octane 
• 1222106-43-5 7-benzyl-4,7-diazaspiro[2.5]octane-5,8-dione 
• 1199792-92-1 4-(trifluoroacetyl)-4,7-diazaspiro[2.5]octane hydrochloride 

Downstream Products

• 886766-28-5 4,7-diazaspiro[2.5]octane-7-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

A 4, 7 - diaza spiro [2.5] octane -7 - formic acid tert-butyl synthetic method

The invention belongs to the technical field of chemical synthesis of N-heterocycle-containing drug intermediates, and particularly relates to a synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate. By using diethyl malonate as a raw material, cyclization reaction, Hofmann reaction, hydrolysis reaction, acylation reaction for recyclization, reduction reaction and the like are performed to conveniently synthesize the target compound product. The method has the advantages of simple synthesis technique, cheap and accessible raw materials, mild reaction conditions, high controllability, low cost and high yield, and is convenient to operate.

Sulfamide derivative and application thereof

The invention relates to a sulfamide derivative and a pharmaceutical composition comprising the compound as well as use of the sulfamide derivative and the pharmaceutical composition as a preparation drug, in particular, use of a drug for preparing a BCL-2 family protein antagonist and use of the drug for treating cancers.

MORPHOLINOPURINE DERIVATIVES

There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

Spiro compound

The present invention relates to spiro compounds of general formula I: STR1 wherein the substituents are herein below defined. The present invention relates to antibacterial spiro compounds which are of value as drugs for humans, veterinary drugs or drugs for use in fish culture or as preservatives, and to antibacterial compositions containing one or more of the same compounds as active ingredients.