99267-72-8

Basic information

• Product Name: (4R,5R)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylethenyl)-1,3-dioxolane
• Synonyms: (4R,5R)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylethenyl)-1,3-dioxolane
• CAS NO: 99267-72-8
• Molecular Weight: 348.396
• Mol File: 99267-72-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4R,5R)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylethenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylethenyl)-1,3-dioxolane(99267-72-8)
• EPA Substance Registry System: (4R,5R)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylethenyl)-1,3-dioxolane(99267-72-8)

Safety Data

• Hazardous Substances Data: 99267-72-8(Hazardous Substances Data)

Upstream product

• 2217-15-4 L-(+)-diisopropyl tartrate 
• 25226-98-6 trans-cinnamaldehyde diethylacetal 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 99267-80-8 (4R,5R)-2-((1R,2R)-2-Phenyl-cyclopropyl)-[1,3]dioxolane-4,5-dicarboxylic acid diisopropyl ester 
• 99267-80-8 (91percentR,9percentS)-(4l,5l,1'u,2'l)-4,5-Bis((2-methylethoxy)carbonyl)-2-(trans-2-phenylcyclopropyl)-1,3-dioxolane 
• 82263-48-7 trans-2- phenylcyclopropane-1-carbaldehyde 
• 158360-21-5 3E-<(1S,2R)-2-phenyl-1-cyclopropyl>-2-propen-1-ol 

Relevant articles and documents

Approaches to the assembly-of the antifungal agent FR-900848: Studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3- dimethyl-4,5-diphenylimidazolidine

Both syn- and anti-bicyclopropane derivatives are efficiently prepared with good relative and absolute stereocontrol; structures are unequivocally determined by an X-ray crystallographic study of the title imidazolidine-derivative.