99274-32-5

Basic information

• Product Name: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-
• CAS NO: 99274-32-5
• Molecular Formula: C11H12O4
• Molecular Weight: 208.214
• Mol File: 99274-32-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(99274-32-5)
• EPA Substance Registry System: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(99274-32-5)

Safety Data

• Hazardous Substances Data: 99274-32-5(Hazardous Substances Data)

Upstream product

• 10257-28-0 D-Galactose 
• 100-52-7 benzaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 3006-41-5 4,6-O-benzylidene-α,β-D-galactopyranose 
• 53131-06-9 1,3-O-benzylidene-D-arabinitol 
• 80924-06-7 1,3-O-benzylidene D-arabitol 
• 59-23-4 D-Galactose 
• 488-82-4 D-Arabitol 

Downstream Products

• 157001-66-6 (2R,3R,4S,5E)-1,3-O-benzylidene-5-dodecene-1,2,3,4-tetrol 
• 157086-55-0 (2S,3R,4R)-1,3-O-benzylidene-5-dodecyne-1,2,3,4-tetrol 
• 157001-56-4 (2S,3R,4S)-1,3-O-benzylidene-5-dodecyne-1,2,3,4-tetrol 
• 117112-62-6 (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol 
• 114275-39-7 (2R,3R,4E)-1,3-benzylidene-4-octadecene-1,2,3-triol 
• 103411-89-8 (2R,3R,4E)-1,3-O-Benzyliden-4-icosadecen-1,2,3-triol 
• 140914-42-7 (2R,3R,4R)-1,3-O-benzylidene-1,2,3,4-dodecanetetrol 
• 140914-41-6 (2R,3R,4S)-1,3-O-benzylidene-1,2,3,4-dodecanetetrol 
• 303752-90-1 1,3-O-benzylidene-(D-arabino/L-xylo)-1,2,3,4-octadecanetetrol 
• 114200-51-0 (2R,3R,4E,8E)-1,3-O-Benzyliden-4,8-octadecadien-1,2,3-triol 
• 103670-20-8 (1R)-2,4-O-Benzylidene-1-C-(dimethoxyphosphoryl)-D-threitol 
• 103411-88-7 (2S,4aR,6R,6aS,8S,10aR,12S,12aS)-2,8-Diphenyl-octahydro-1,3,5,7,9,11-hexaoxa-dibenzo[a,e]cyclooctene-6,12-diol 
• 951787-30-7 1,1-dibenzyl-2-(((2S,4R,5R)-5-hydroxy-2-phenyl-1,3-dioxan-4-yl)methylene)hydrazine 
• 1004994-84-6 (E)-ethyl 3-((2S,4R,5R)-5-hydroxy-2-phenyl-1,3-dioxan-4-yl)acrylate 

Relevant articles and documents

An Improved, Versatile, and Easily Scalable Synthesis of Sphingomyelins: Application to Stable Isotope Labeling

With a view to make conveniently labeled mass spectrometry standards available, a set of deuterated sphingomyelins were prepared by a new expedient, flexible, robust, scalable, and high-yielding synthetic scheme starting from 2-azido-3- O -benzoylsphingos

4,5-Cis Unsaturated α-GalCer Analogues Distinctly Lead to CD1d-Mediated Th1-Biased NKT Cell Responses

The total synthesis of 4,5-cis unsaturated α-GalCer analogues was achieved, and their immune-response altering activity was assessed in vitro as well as in vivo in mice. Using glycosyl iodide as a glycosyl donor, construction of the sphingosine unit was shortened by four steps and single α-stereoselectivity was achieved in good yield (67%). With regard to the therapeutic use of α-GalCer, the novel analogues (1b and 1c) distinctly induced a Th1-biased cytokine response, avoiding induction of a contradictory response and overstimulation.

Synthesis of a 1α-C-methyl analogue of 25-hydroxyvitamin D3: interaction with a mutant vitamin D receptor Arg274Leu

Vitamin D3 analogues have been developed for a mutant vitamin D receptor (VDR), Arg274Leu. The mutant VDR has a mutation at Arg274, which forms an important hydrogen bond with 1α-OH of 1α,25-dihydroxyvitamin D3 to anchor the ligand t