610-36-6

Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-2-nitrobenzoic acid is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex drug molecules, enhancing the development of new medications.
Used in Dye Industry:
4-Amino-2-nitrobenzoic acid is used as an intermediate in the synthesis of dyes, leveraging its chemical properties to create a range of colorants for various applications.
Used in Organic Chemistry Research:
4-Amino-2-nitrobenzoic acid is used as a reagent and building block in organic chemistry research, facilitating the production of diverse organic compounds for scientific exploration and commercial applications.
Used in Manufacturing of Fine Chemicals:
4-Amino-2-nitrobenzoic acid is used as a raw material in the manufacturing of fine chemicals, contributing to the creation of specialty products that require precise chemical structures.

InChI:InChI=1/C7H6N2O4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,8H2,(H,10,11)

Upstream product

• 610-30-0 2,4-dinitrobenzoic acid 
• 64-17-5 ethanol 
• 7803-57-8 hydrazine hydrate 
• 7647-01-0 hydrogenchloride 
• 21573-29-5 4-acetylamino-2-nitrobenzoic acid 
• 28144-70-9 anthranilic acid amide 
• 121-14-2 2,4-dinitrotoluene 
• 342045-62-9 4-acetylamino-6-nitro-isophthalic acid 
• 7664-93-9 sulfuric acid 
• 84228-46-6 4-amino-2-nitrobenzoic acid ethyl ester 
• 2719-14-4 4-acetylamino-2-nitrotoluene 

Downstream Products

• 84228-46-6 4-amino-2-nitrobenzoic acid ethyl ester 
• 171116-84-0 N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide 
• 54558-79-1 4-(methylthio)-2-nitrobenzoic acid 
• 1072161-38-6 2'-[18F]fluoro-folic acid 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 171116-88-4 4-(2-nitrobenzamido)2-nitrobenzoic acid 
• 910235-74-4 4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid [3-(6-{4-[(2-hydroxy-ethyl)-methyl-carbamoyl]-3-nitro-phenylamino}-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl)-2-methyl-phenyl]-amide 
• 910232-80-3 4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid [3-(6-{3-amino-4-[(2-hydroxy-ethyl)-methyl-carbamoyl]-phenylamino}-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl)-2-methyl-phenyl]-amide 
• 910233-94-2 N-(3-{6-[3-amino-4-(morpholine-4-carbonyl)-phenylamino]-4-methyl-5-oxo-4,5-dihydro-pyrazin-2-yl}-2-methyl-phenyl)-4-tert-butyl-benzamide 
• 910234-22-9 4-(tert-butyl)-N-(2-methyl-3-(1-methyl-5-((4-(morpholine-4-carbonyl)-3-nitrophenyl)amino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)benzamide 

Relevant academic research and scientific papers

The detection of glycine from the treatment of glyoxylic acid with iron(II) sulfate and ammonia in water

A glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.

3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS

A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14; aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10; alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14; aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.

Optical element and compounds used in its manufacture

An optical frequency conversion element has a wave-guiding layer which consists of a χ(2) -active ferroelectric liquid crystal. The monomeric or polymeric liquid crystal material has a periodic structure which permits the so-called quasi phase matching of a guided laser beam. The period length of the structure is equal to twice the coherence length lc =?/Δβ of the material, whereby Δβ=βo (2ω)-2βo (ω), with ω=angular frequency of the fundamental wave, 0=zero-order mode and β=propagation constant of the mode.

2-ureido-benzamide derivatives

This invention is concerned with 2-ureido-benzamide compounds of the formula (1) STR1 in which R1 is H, halogen atom, (C1 -C4)alkyl, (C1 -C4)alkoxy or (C1 -C4)dialkylamino and R2 is H, halogen atom, hydroxy, nitro, (C1 -C4)alkyl, (C1 -C4)alkoxy, (C3 -C6) cycloalkylmethoxy, (C1 -C4) alkylthio, (C1 -C4) alkylsulfinyl, (C1 -C4)alkylsulfonyl or STR2 wherein j is an integer of from 0 to 2 and R3 and R4 are each independently H, (C1 -C4)alkyl, (C1 -C4)alkanoyl, (C1 -C4)alkylsulfonyl or (C1 -C4)alkylcarbamoyl, NR3 R4 can to form a pyrrolidine, piperidine, morpholine, imidazole or pyrazole ring; X is a (C3 -C15)alkyl, (C3 -C6) cycloalkyl, (C3 -C6) cycloalkylmethyl, ω-(C1 -C4) alkoxy-(C1 -C4) alkyl group or STR3 wherein k is an integer of from 1 to 4 and R5 and R6 are each independently H, Y is H or (C1 -C4)alkyl and Z is STR4 wherein m is an integer of from 0 to 4.

Synthesis of reference substances for highly polar metabolites of nitroaromatic compounds

Transformation processes of nitroaromatic compounds (NAC) lead to polar and highly hydrophilic metabolites. For the unequivocal identification of proposed metabolites reference substances are needed. Since most of them are not commercially available, their synthesis was done in our group. In many cases no satisfying synthesis schemes were found in the literature. In this communication, we therefore describe the preparation, structural elucidation and separation of 17 compounds. Many of the newly synthesized analytes were found in various water samples from a former ammunition plant.

Benzyl-piperidine derivatives

Benzly-piperidine derivatives of formula I and their pharmaceutically acceptable salts are used in the control of psychotic disorders which are caused by damage to the dopamine system, especially schizophrenia. STR1 A is STR2 B is STR3 R 1, R 2 and R 3 are independently hydrogen, amino, nitro, halogen, lower-alkly or lower-alkoxy. R 4, R 5 and R 6 are independently hydrogen, nitro, halogen, lower-alkyl, lower-alkoxy, cyano, trifluoromethyl, amino, lower-alkylamino or di-lower-alkylamino. R 7, R 2 and R 9 are independently hydrogen, amino or nitro.