99291-16-4

Usage

Usage

Precursor in the synthesis of various organic compounds and pharmaceuticals

Physical State

Colorless, odorless liquid

Solubility

Soluble in water

Boiling Point

Relatively low

Properties

Antioxidant

Applications

Production of certain types of resins and polymers

Safety Concerns

Potential for skin, eye, and respiratory system irritation

Handling

Must be handled with care and in accordance with safety protocols

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 75-26-3 isopropyl bromide 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 75141-84-3 (S)-3-(2-Bromo-phenyl)-2-phenyl-hexahydro-pyrrolo[1,2-c]imidazole 
• 6630-33-7 ortho-bromobenzaldehyde 
• 75141-87-6 (3S)-3-isopropyl-1,3-dihydro-isobenzofuran-1-ol 
• 920-39-8 isopropylmagnesium bromide 
• 64002-57-9 3-(methylethyl)-1(3H)-isobenzofuranone 
• 1068-55-9 isopropylmagnesium chloride 
• 5652-58-4 2-carboxyisobutyrophenone 

Downstream Products

• 117436-88-1 isopropyl-2 (2H) isobenzofuranne 
• 99291-14-2 α-(2-propyl)-α,α'-dibromoxylene 
• 131035-32-0 Acetic acid (S)-1-(2-acetoxymethyl-phenyl)-2-methyl-propyl ester 

Relevant academic research and scientific papers

Optical resolution of C2-symmetric racemic 1,4-diols with o-xylylene structure by chiral resolving agent (S)-ALBO-V

Optical resolution of C2-symmetric racemic 1,4-diols, 1,2-bis(1-hydroxyalkyl)benzene, was examined using (S)-5-allyl-2-oxabicyclo[3.3.0]octene ((S)-ALBO-V) as chiral resolving agent. Diastereomeric acetals obtained from the 1,4-diols with (S)-A

Synthesis of α,β-unsaturated dioxanes, dioxolanes and dioxepanes by trans-acetalisation of dimethylacetals with meso or C 2-symmetrical 1,2-, 1,3- and 1,4-diols

Several o-dibenzylic diols were prepared reacting organometallics with o-phthalaldehyde at room temperature in ether. The identity of the meso and C2-symmetrical (D,L) isomers as well as their ratio were determined by chiral gas chromatography. The meso and C2 (racemic) stereoisomeric diols were easily separated by flash chromatography on silica gel. A set of 18 α,β-unsaturated acetals were then prepared reacting those, as well as commercially available 1,2, 1,3 and 1,4 diols, with the corresponding methylacetals in acidic medium. A trans-acetalisation procedure adapted to the cases of fragile allylic alcohols or unfavorable 1,6 diols-derived dioxonanes based on a Dean-Stark trapping of methanol was also employed.

4,5 Dihydroimidazole compounds which have useful pharmaceutical utility

A compound of formula (I): STR1 or a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein: Z represents a residue of a substituted or unsubstituted aryl group, A1 represents a subst

REACTIONS STEREOSELECTIVES DES ALKYLMAGNESIENS SECONDAIRES AVEC LES ANHYDRIDES ET LACTONES RIGIDES

High stereoselectivity was observed in the reactions of secondary alkylmagnesium compounds with bicyclohept-5-ene-2,3-dicarboxylic anhydride 1 and lactone 2 leading respectively to the formation of trans diastereomeric lactones and erythro primary-secondary diols.

ENANTIOFACE-DIFFERENTIATING ADDITION OF A CHIRAL ARYLLITHIUM REAGENT TO ALDEHYDES

A chiral aryllithium reagent was prepared by treating a chiral aminal, derived from (S)-2-(anilinomethyl)pyrrolidine and o-bromobenzaldehyde, with n-butyl lithium.The chiral reagent reacted highly enantioface selectively with aliphatic aldehydes and, on h