99304-36-6Relevant academic research and scientific papers
Cooperative Heterobimetallic Zinc/Alkaline Earth Metal Catalysis: A Zn/Sr Aminophenol Sulfonamide Complex for Catalytic Asymmetric Michael Addition of 3-Acetoxy-2-oxindoles to β-Ester Enones
Yang, Yuchen,Tang, Cheng,Liang, Guojuan,Deng, Ping,Zhou, Jing,Yang, Zinan,Chen, Peng,Zhou, Hui
, p. 7119 - 7130 (2021)
A heterobimetallic zinc/strontium catalyst has been developed for the asymmetric Michael addition of 3-acetoxy-2-oxindoles to β-ester enones in high yields with excellent enantioselectivities and high diastereoselectivities. This process represents that 3-acetoxy-2-oxindoles can be used as a stable air- and base-tolerant precursor for chiral 3-substituted 3-hydroxy-2-oxindoles.
