99358-22-2Relevant academic research and scientific papers
Antineoplastic agents. 561. Total synthesis of respirantin
Pettit, George R.,Smith, Thomas H.,Feng, Song,Knight, John C.,Tan, Rui,Pettit, Robin K.,Hinrichs, Peter A.
, p. 1073 - 1083 (2007)
Total synthesis of the 18-membered ring cyclodepsipeptide believed to be respirantin (1b) has been achieved. The key step in the synthesis is an intramolecular transesterification of the β-ketoester alcohol 6 to afford the protected macrocycle 5. The synt
Antidiabetic agents
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, (2008/06/13)
A compound of the formula wherein n, m, Z, R1, R5, R8, R9, R10 and R11 are as defined above, useful in the treatment of diabetes, insulin resistance, diabetic neuropathy, diabetic nephropat
Antidiabetic agents
-
, (2008/06/13)
A compound of the formula wherein n, m, Z, R1, R5, R8, R9, R10 and R11 are as defined above, useful in the treatment of diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, and tissue ischemia, particularly myocardial ischemia.
