3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester

Base Information

Chemical Name:3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester
CAS No.:99358-22-2
Molecular Formula:C9H9NO4
Molecular Weight:195.175
Hs Code.:
DSSTox Substance ID:DTXSID901273784

Synonyms:99358-22-2;3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester;SCHEMBL4753944;IVZHVURLFFLICH-UHFFFAOYSA-N;DTXSID901273784;Methyl 3-(formylamino)-2-hydroxybenzoate

Suppliers and Price of 3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:195.05315777
Heavy Atom Count:14
Complexity:219

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C(=CC=C1)NC=O)O

Technology Process of 3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester

There total 4 articles about 3-Formylamino-2-hydroxy-benzoic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 17968-71-7
2-hydroxy-3-formylaminobenzoic acid

: 74-88-4
methyl iodide

: 99358-22-2
methyl 2-hydroxy-3-formylaminobenzoate

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 23 ℃; for 15h;
DOI:10.1021/np0680735

Reference yield:

: 35748-34-6
methyl 3-aminosalicylate

: 99358-22-2
methyl 2-hydroxy-3-formylaminobenzoate

Guidance literature:: With sodium formate; In concentrated formic acid;

Reference yield:

: 570-23-0
3-aminosalicylic acid

: 99358-22-2
methyl 2-hydroxy-3-formylaminobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 0.5 h / 150 °C

2: 79 percent / NaHCO₃ / dimethylformamide / 15 h / 23 °C

With sodium hydrogencarbonate; In N,N-dimethyl-formamide;
DOI:10.1021/np0680735