99358-44-8Relevant academic research and scientific papers
Synthesis, structure, and antibacterial evaluation of new N-substituted-3-amino- 5-oxo-4-phenyl-2,5-dihydro-1 H-pyrazole-1-carbothioamides
Pitucha, Monika,Mazur, Liliana,Kosikowska, Urszula,Pachuta-Stec, Anna,Malm, Anna,Popiolek, Lukasz,Rzaczynska, Zofia
, p. 215 - 221 (2010)
Novel N-substituted-3-amino-5-oxo- 4-phenyl-2,5-dihydro-1 H-pyrazole-1-carbothioamide derivatives were synthesized by means of two methods. First is the cyclization reaction of 1- (cyanophenyl)acetyl-4- substituted thiosemicarbazide, and the second one is
Inhibitory effect of N-ethyl-3-amino-5-oxo-4-phenyl-2,5-dihydro-1H- pyrazole-1-carbothioamide on Haemophilus spp. planktonic or biofilm-forming cells
Kosikowska, Urszula,Malm, Anna,Pitucha, Monika,Rajtar, Barbara,Polz-Dacewicz, Malgorzata
, p. 1057 - 1066 (2014/03/21)
During this study, we have investigated in vitro activity of N-substituted-3-amino-5-oxo-4-phenyl-2,5-dihydro-1H-pyrazole-1-carbothioamide derivatives with N-ethyl, N-(4-metoxyphenyl) and N-cyclohexyl substituents against Gram-negative Haemophilus influen
Experimental and computational studies on the tautomerism of N-substituted 3-amino-5-oxo-4-phenyl-1H-pyrazolo-1-carboxamides with antibacterial activity
Kaczor, Agnieszka A.,Wróbel, Tomasz,Karczmarzyk, Zbigniew,Wysocki, Waldemar,Mendyk, Ewaryst,Poso, Antti,Matosiuk, Dariusz,Pitucha, Monika
, p. 188 - 196 (2013/10/08)
The tautomerism of N-substituted 3-amino-5-oxo-4-phenyl-1H-pyrazolo-1- carboxamides with antibacterial activity is studied with X-ray crystallography, IR, 1H and 13C NMR (including NOESY spectra) and quantum chemical calculations. It
Selective method for the preparation of isomeric N-alkyl and N-aryl-3(5)-amino-5(3)-hydroxy 1H-pyrazole-1-carboxamides
Drummond,Johnson
, p. 1123 - 1127 (2007/10/02)
As part of a program to develop novel mechanism based skeletal muscle relaxants we identified 5-amino-3-hydroxy-1H-pyrazole-1-carboxyamide (1) as a potential structural lead. This highly functionalized pyrazole was prepared via a published procedure [1] (
