99367-73-4

Basic information

• Product Name: 5-Amino-4-isopropylidene-2-(2,4,6-trichloro-phenyl)-2,4-dihydro-pyrazol-3-one
• CAS NO: 99367-73-4
• Molecular Weight: 318.59
• Mol File: 99367-73-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Amino-4-isopropylidene-2-(2,4,6-trichloro-phenyl)-2,4-dihydro-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-4-isopropylidene-2-(2,4,6-trichloro-phenyl)-2,4-dihydro-pyrazol-3-one(99367-73-4)
• EPA Substance Registry System: 5-Amino-4-isopropylidene-2-(2,4,6-trichloro-phenyl)-2,4-dihydro-pyrazol-3-one(99367-73-4)

Safety Data

• Hazardous Substances Data: 99367-73-4(Hazardous Substances Data)

Upstream product

• 27241-31-2 3-amino-1-(2',4',6'-trichlorophenyl)-4,5-dihydropyrazol-5(1H)-one 
• 67-64-1 acetone 

Downstream Products

• 99367-80-3 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one 

Relevant articles and documents

A New Synthesis of 4,5-Dihydroxy-pyrazoles

1-Aryl-pyrazolin-5-ones 1 are converted by Knoevenagel condensation with acetone or by reaction with 2,2-dimethyl-1,3-dioxolane 6 to 1-aryl-4-isopropyliden-pyrazolin-5-ones 2.The compounds 2 are epoxidized by hydrogen peroxide forming the spiro-epoxides 3, which can be cleaved to 4,5-dihydroxy-pyrazoles 4 under acidic conditions. 4-Acetoxy-5-hydroxy-pyrazoles 13 are formed directly, when 3 are cleaved in presence of acetic anhydride.The 3,3',3'-trimethyl-1-(4-nitro-phenyl)-pyrazolin-4-spiro-2'-oxiran-5-one 3b undergoes rearrangement to the 1,3-dioxolopyrazole 12.