99367-80-3

Basic information

• Product Name: 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one
• Synonyms: 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one
• CAS NO: 99367-80-3
• Molecular Weight: 334.589
• Mol File: 99367-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one(99367-80-3)
• EPA Substance Registry System: 7-Amino-2,2-dimethyl-5-(2,4,6-trichloro-phenyl)-1-oxa-5,6-diaza-spiro[2.4]hept-6-en-4-one(99367-80-3)

Safety Data

• Hazardous Substances Data: 99367-80-3(Hazardous Substances Data)

Upstream product

• 27241-31-2 3-amino-1-(2',4',6'-trichlorophenyl)-4,5-dihydropyrazol-5(1H)-one 
• 99367-73-4 5-Amino-4-isopropylidene-2-(2,4,6-trichloro-phenyl)-2,4-dihydro-pyrazol-3-one 

Downstream Products

• 23914-43-4 2,2',4,4',6,6'-Hexachlor-azobenzen 
• 33422-33-2 N-Benzoyl-N'-(2,4,6-trichlor-phenyl)hydrazin 
• 2724-66-5 2,4,6-trichlorophenylhydrazine hydrochloride 
• 108-70-3 1,3,5-trichlorobenzene 
• 104891-98-7 3-Amino-3-(2,4,6-trichlor-phenylazo)propensaeuremethylester 

Relevant articles and documents

A New Synthesis of 4,5-Dihydroxy-pyrazoles

1-Aryl-pyrazolin-5-ones 1 are converted by Knoevenagel condensation with acetone or by reaction with 2,2-dimethyl-1,3-dioxolane 6 to 1-aryl-4-isopropyliden-pyrazolin-5-ones 2.The compounds 2 are epoxidized by hydrogen peroxide forming the spiro-epoxides 3, which can be cleaved to 4,5-dihydroxy-pyrazoles 4 under acidic conditions. 4-Acetoxy-5-hydroxy-pyrazoles 13 are formed directly, when 3 are cleaved in presence of acetic anhydride.The 3,3',3'-trimethyl-1-(4-nitro-phenyl)-pyrazolin-4-spiro-2'-oxiran-5-one 3b undergoes rearrangement to the 1,3-dioxolopyrazole 12.