99372-97-1

Usage

Physical state

Yellowish liquid

Odor

Faint

Usage

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Functional groups

Contains a cyano group (–C≡N) and a cyclic ketone group

Reactions

Can undergo alkylation, acylation, and nucleophilic addition

Derivatives

Can produce substituted cyanocyclopentanones

Importance

Serves as a versatile intermediate in the production of diverse chemical compounds.

Upstream product

• 75-03-6 ethyl iodide 
• 2941-29-9 2-oxocyclopentanecarbonitrile 

Downstream Products

• 1135993-54-2 2-ethyl-2-phenylsulfanyl-cyclopentanone 
• 99373-03-2 ethyl-2 oxo-6 hexene-2 (Z) carbonitrile-1 
• 99373-02-1 ethyl-2 oxo-6 hexene-2 (E) carbonitrile-1 

Relevant academic research and scientific papers

Lithium naphthalenide induced reductive alkylation of α-cyano ketones. A general method for regiocontrol of α,α-dialkylation of ketones

An efficient general method for the consecutive introduction of two alkyl groups to the α carbon of a ketone carbonyl has been developed, making use of the lithium naphthalenide induced reductive alkylation of an α-cyano ketone system as a key operation.

Comportement photochimique d'alkyl-1 oxo-2 cyclopentanecarbonitriles-1. Preparation d'olefines bifonctionnelles

The photochemical reactivity of a number of 2-cyano 2-alkylcyclopentanones 4 was studied and found to depend on the nature of the alkyl group R.When R is CH3 or C2H5, the only products are the E and Z α,β unsaturated cyano-aldehydes 5.